Abstract:Lesion-behavior mapping (LBM) provides a statistical map of the association between voxel-wise brain damage and individual differences in behavior. To understand whether two behaviors are mediated by damage to distinct brain regions, researchers often compare LBM beta weight outputs by either the overlap method (emphasizing differences) or by the correlation method (emphasizing similarity). However, both methods lack a principled way to determine LBM distinctness and are disconnected from a major goal of LBMs,… Show more
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