Using post transplant 1 week Tc-99m DTPA renal scan as another method for predicting renal graft failure

Chong, Ari; Ha, Jung‐Min; Choi, Nam Kyu; Shin, Min Ho

doi:10.1515/med-2019-0056

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…Perfusion and parenchymal kinetic parameters (T1/2 washout, ΔP and accumulation index) in DRSG with [ 99m Tc] Tc-DTPA had prognostic value also for assessing long-term graft function (up to 5 years) [17,34].…”

Section: Prognostic Significance Of Scintigraphy For Renal Transplant...mentioning

confidence: 99%

Significance of nuclear medicine methods for diagnosis and predicting the course of renal transplantation complications

Satyr,

Noverko,

Pantus

et al. 2024

CSIC

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Renal transplantation is a replacement-based therapeutic method in end-stage kidney failure.It is based on the interdisciplinary collaboration between scientists and clinicians, which match together the achievements of surgery, immunology, and radiation diagnostics. After transplantation the complications appear, which can be associated with status of the graft, the immunological factors of compatibility between the donor and the recipient, the surgical intervention. Early diagnosis and forehanded treatment of such complications is important, as it helps to evaluate and predict the functionality of the graft. In this article we discuss the complications after kidney transplantation: the reasons of their occurrence, pathogenesis, clinical features, and radiation imaging signs. The opportunities of the radiology methods for the differential diagnostics of complications which appear before, during or after the surgery, are shown. We pay the main attention to the nuclear medicine methods, especially the dynamic renal scintigraphy (DRSG) as a method for the evaluation of graft functionality. This is a safe, accessible and non-invasive method for evaluation the quantitative and qualitative parameters of kidney function. DRSG consequently characterizes the perfusion, the extraction and the excretion in the studied organ. We display the standard DRSG protocols using [99mTc] Tc-MAG3 and [99mTc] Tc-DTPA radiopharmaceuticals. We analyze investigations of kinetic perfusion and parenchymal DRSG parameters and their importance for differential diagnosis of complications, prognosis on delayed and slow graft function, short-term and long-term graft functionality assessment. We make an accent on the prognostic importance of the dynamic changes visible on DRSG. We discuss the perspectives of further development of scintigraphic methods for the assessment of kidney grafts. It is related to the implementation of high-quality 3-dimentional visualization, newest radiopharmaceuticals. We conclude the importance of the nuclear medicine as an element of multidisciplinary approach in transplantology.

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Section: Prognostic Significance Of Scintigraphy For Renal Transplant...mentioning

confidence: 99%

Significance of nuclear medicine methods for diagnosis and predicting the course of renal transplantation complications

Satyr,

Noverko,

Pantus

et al. 2024

CSIC

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Deceased vs. living donor kidney transplantation in prediction of acute renal allograft rejection using Tc-99m DTPA renal scan

et al. 2020

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Using post transplant 1 week Tc-99m DTPA renal scan as another method for predicting renal graft failure

Abstract: AbstractPurposeThe aims of this study were to determine whether post transplant renal scan performed at around 1 week can predict graft failure, and to identify the best predictive factors among easy-to-measure variables.Materials and methodsWe retrospectively evaluated… Show more

Cited by 2 publications

References 16 publications

Significance of nuclear medicine methods for diagnosis and predicting the course of renal transplantation complications

Significance of nuclear medicine methods for diagnosis and predicting the course of renal transplantation complications

Deceased vs. living donor kidney transplantation in prediction of acute renal allograft rejection using Tc-99m DTPA renal scan

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