Using Patient-Reported Outcomes in Schizophrenia: The Scottish Schizophrenia Outcomes Study

Abstract

This study has demonstrated that it is feasible within the Scottish NHS to routinely collect meaningful outcomes data in schizophrenia. Patient-reported assessments were also successfully collected and used in care plans. This model shows that it is possible to incorporate patient-reported assessments into routine care for schizophrenia. Such assessments may provide useful data for clinicians and may improve treatment adherence. The pattern of outcomes and interventions confirms that despite the introduction of guidelines, new treatments, and new services, people with schizophrenia continue to have high levels of chronic disability.

The impact of co-morbid personality disorder on use of psychiatric services and involuntary hospitalization in people with severe mental illness

“…We rated for the presence and severity of symptoms, as well as social functioning problems using the Health of the Nations Outcome Scale (HoNOS), a well-validated, 12-item, clinician-administered measure [19][20] [21]. Eight of the 12 items assess clinical symptoms-(1) overactive, aggressive, disruptive or agitated behaviour; (2) non-accidental self-injury; (3) problem-drinking or drug-taking; (4) cognitive problems; (5) physical illness or disability problems; (6) problems associated with hallucinations and delusions; (7) problems with depressed mood; (8) other mental and behavioural problems.…”

Cognitive Impairment Associated with Schizophrenia: A Review of the Humanistic Burden

“…C l i n i c i a n -r e p o r t e d o u t c o m e s a n d performance on cognitive tasks are important in assessing patient prognosis and treatment efficacy. However, the patient perspective can also provide valuable insights [25,26] and may provide a link between cognitive performance and the patient's actual level of real-world functioning [27]. To date, patient-reported outcomes (PRO) instruments have not been evaluated for assessing treatments for CIAS.…”

Clozapine-induced interstitial nephritis - a rare but important complication: a case report

“…Treatment resistance in schizophrenia has been estimated to be around 30% [7], and increasing numbers of patients are being prescribed clozapine; for example, in the Scottish Schizophrenia Outcomes Study [8], 40% of the cohort of 1015 patients was prescribed clozapine. Given the limited efficacy of current antipsychotics, it is likely that increasing numbers of patients may be treated with clozapine.…”