Using
            <i>Entamoeba muris</i>
            To Model Fecal-Oral Transmission of
            <i>Entamoeba</i>
            in Mice

Cavazos, Carolina Mendoza; Heredia, Marienela Y.; Owens, L.; Knoll, Laura J.

doi:10.1128/mbio.03008-22

Search citation statements

Order By: Relevance

Paper Sections

Select...

Life Cycle Of Giardia1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article1

Book1

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The trophozoite stage is responsible for the symptoms of giardiasis, which include diarrhea, abdominal pain, and bloating. After several days in the host's small intestine, the trophozoites undergo a process called encystation (Mendoza Cavazos et al 2023). During this process, the trophozoites transform back into cysts, which are then passed out of the host in the feces (Smoguła et al 2023).…”

Section: Life Cycle Of Giardiamentioning

confidence: 99%

Cryptosporidiosis and Giardiasis: Two Common Foodborne Parasitic Infections

2023

IJAB

View full text Add to dashboard Cite

Section: Life Cycle Of Giardiamentioning

confidence: 99%

Cryptosporidiosis and Giardiasis: Two Common Foodborne Parasitic Infections

2023

IJAB

View full text Add to dashboard Cite

Animal Modeling of Infectious Diseases

Afifi,

Al-Rabia,

Fallatah

2024

Animal Models in Experimental Medicine

View full text Add to dashboard Cite

Animal models have been, and continue to be, viable tools for investigating crucial scientific issues related to the pathogenesis of infectious diseases and serve as living platforms for testing novel therapeutics and/or vaccines. The use of animal models in studying infectious diseases is not only founded on the substantially shared biology of most mammals but also on the fact that many human infections are zoonotic, affecting a range of animal species. However, it is noticeable that the results retrieved from animal studies are not always reproducible in studies conducted on humans. The reliability of correlating data from animal models and translating them to human disease succeeds only in well-designed models where their relevance to the investigated human disease is well recognized. Preferable animal models respond similarly to the infectious agent as in humans, where the host’s interaction with the pathogen creates the same immunological and molecular environment. Several animal models have been designed to investigate the different aspects of the infectious process, such as biology, immunology, and pathogenesis. The murine model has been chosen for most studies investigating infectious diseases. Despite the limitations of the current animal models, remarkable progress has been achieved using these models, including a better understanding of host immune responses to infection, microbiome–pathogen interactions, the molecular mechanisms underlying tissue damage as well as validation of novel therapeutics and vaccine development.

show abstract

Using Entamoeba muris To Model Fecal-Oral Transmission of Entamoeba in Mice

Cited by 2 publications

References 47 publications

Cryptosporidiosis and Giardiasis: Two Common Foodborne Parasitic Infections

Cryptosporidiosis and Giardiasis: Two Common Foodborne Parasitic Infections

Animal Modeling of Infectious Diseases

Contact Info

Product

Resources

About