The purpose of this study was to examine Mainstreaming Disaster Risk Reduction in the Curricular of Colleges of Education in Ghana. Mixed method approach and cross-sectional research design were employed in the study. Population of the study comprised all Social Studies teacher trainees, Principals and tutors of the Colleges of Education, officers of the Ghana Education Service and NADMO officials. Purposive sampling technique was used to select 319 Social Studies teacher trainees (99 students from St. Monicas, 67 from Berekum, 73 from Tamale and 80 from John Bosco) Eight (8 Social Studies tutors, four (4) principals, four (4) personnel from the human resource unit of GES of each district, and four (4) NADMO officials. The main instruments used for data collection were questionnaires and interview guide. The study revealed that the extent of the coverage of DRR issues in the curricula of the colleges of education was low. This development leads to a low level of usage of DRR kits and the organization of extracurricular activities on DRR for students. The study also concluded that both teacher trainees and the officials of the Ghana Education Service appreciate the low level of the coverage of DRR in the teaching curricula and the need to take pragmatic measures to address the gaps. It is recommended that, NaCCa, Universities mentoring the colleges of education in Ghana, the Ministry of Education, through the GES, should consider mainstreaming DRR in the curricula of the colleges of education by developing a full subject on DRR for students. This will give teacher trainees and the pupils they teach an in-depth knowledge about disasters and how they could be mitigated. Emphasis should also be placed on how teacher trainees will impact the knowledge to students through the use of logistics and field work.