Using EQ-5D-3L and OAB-5D to assess changes in the health-related quality of life of men with lower urinary tract symptoms associated with benign prostatic hyperplasia

Abstract

A large ceiling effect on EQ-5D-3L substantially limited its sensitivity in this population. OAB-5D proved more sensitive to changes in health status and could be considered a complement to ED-5D-3L as a source of utilities for health economic modelling.

Real‐world assessment and characteristics of men with benign prostatic hyperplasia (BPH) in primary care and urology clinics in Spain

“…1,2 By obstructing urinary flow, BPH frequently causes lower urinary tract symptoms (LUTS), which are a significant burden in ageing men, and have a major negative impact on quality of life (QoL); it also increases the risk of disease progression. 1,[3][4][5][6][7] Although BPH is the most common cause of LUTS, other possible causes exist; therefore, comprehensive assessment facilitating an accurate diagnosis of BPH as a cause of LUTS is crucial. [8][9][10][11] As per clinical guidelines in Spain, the following assessments are mandatory: clinical history, physical exam, digital rectal exam (DRE) and urinalysis; and the following assessments are recommended: prostate-specific antigen (PSA) and International Prostate Symptom Score (IPSS).…”

“…Benign prostatic hyperplasia (BPH) is a progressive, non‐malignant overgrowth of the prostate gland commonly observed in men over 50 years of age 1,2 . By obstructing urinary flow, BPH frequently causes lower urinary tract symptoms (LUTS), which are a significant burden in ageing men, and have a major negative impact on quality of life (QoL); it also increases the risk of disease progression 1,3‐7 …”

Self-Care and Quality of Life in Elderly Chinese Patients with Benign Prostatic Hyperplasia

“…An estimated 50% of men have pathological signs of BPH in the 51-60 age group, a proportion that increases to more than 70% among men in the 61-70 age group. The enlarged prostate might cause bothersome LUTS, requiring treatment with medication or surgery or both (Hakimi et al, 2017). The results of self-care agency in this study showed that the mean ESCA scale score of elderly patients with BPH was 110.01 and that 58.6% of the participants were at the middle level with regard to self-care agency.…”

Longitudinal study of patients’ health-related quality of life using EQ-5D-3L in 11 Swedish National Quality Registers

“…PCHC has been employed in other studies to document change over time in various diseases, such as heart failure, prostate cancer, diabetes mellitus and overactive bladder. [44][45][46][47][48] The change for the fracture patients cannot be compared directly to changes for other patient groups due to the recall technique used to value health state before injury.…”