Using DNA to develop a profile of phenotypic characteristics of historic period human remains

Elkins, Kelly M.; Kollmann, Dana D.; Bowie, Paige; Chart, Tess; Gorr, Karissa K.; Hutson, Brianna; Kiesel, Brianna D.; Klavens, Adam; Zeller, Cynthia B.

doi:10.1016/j.fsigss.2022.10.066

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…aged bones that partially failed STR profiling) were tested with the ForenSeq TM DNA Signature Prep Kit and gave full STR profiles and indications on ancestry and phenotype prediction for the majority of the samples analyzed. Elkins et al [346] used the same kit and obtained biogeographical ancestry prediction from 15 historic human samples from 1600 to 1700s (tooth, temporal bone, femur, and tibia) and phenotype predictions of eye, hair and skin color from four samples (tooth, temporal bone, femur and fibula).…”

Section: Proteomics For Personal Identificationmentioning

confidence: 99%

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From flesh to bones: Multi‐omics approaches in forensic science

Procopio,

Bonicelli

2024

Proteomics

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Recent advancements in omics techniques have revolutionised the study of biological systems, enabling the generation of high‐throughput biomolecular data. These innovations have found diverse applications, ranging from personalised medicine to forensic sciences. While the investigation of multiple aspects of cells, tissues or entire organisms through the integration of various omics approaches (such as genomics, epigenomics, metagenomics, transcriptomics, proteomics and metabolomics) has already been established in fields like biomedicine and cancer biology, its full potential in forensic sciences remains only partially explored. In this review, we have presented a comprehensive overview of state‐of‐the‐art analytical platforms employed in omics research, with specific emphasis on their application in the forensic field for the identification of the cadaver and the cause of death. Moreover, we have conducted a critical analysis of the computational integration of omics approaches, and highlighted the latest advancements in employing multi‐omics techniques for forensic investigations.

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Section: Proteomics For Personal Identificationmentioning

confidence: 99%

“…Elkins et al. [346] used the same kit and obtained biogeographical ancestry prediction from 15 historic human samples from 1600 to 1700s (tooth, temporal bone, femur, and tibia) and phenotype predictions of eye, hair and skin color from four samples (tooth, temporal bone, femur and fibula). Ambers et al.…”

Section: Omics In Forensic Sciencesmentioning

confidence: 99%