To develop a deep learning model for detecting brain abnormalities on MRI.
Materials and Methods:In this retrospective study, a deep learning approach using T2-weighted fluid attenuated inversion recovery (FLAIR) images was developed to classify brain MRI as "likely normal" or "likely abnormal." A convolutional neural network model was trained on a large heterogeneous dataset collected from two different continents and covering a broad panel of pathologies including neoplasms, hemorrhage, infarcts, and others. Three datasets were used. Dataset A consisted of 2839 patients, Dataset B consisted of 6442 patients, and Dataset C consisted of 1489 patients and was only used for testing. Dataset A and B were split into training, validation and test sets. A total of three models were trained: Model A (using only Dataset A), Model B (using only Dataset B), and Model A+B (using training datasets from A and B). All three models were tested on subsets from Dataset A, Dataset B and Dataset C separately. The evaluation was performed using annotations based on the images as well as labels based on the radiologic reports.