Using concepts in literature‐based discovery: Simulating Swanson's Raynaud–fish oil and migraine–magnesium discoveries

Weeber, Marc; Klein, Harold P.; Berg, Lolkje Theodora Wilhelmina de Jong-van den; Vos, Rein

doi:10.1002/asi.1104.abs

Cited by 119 publications

(171 citation statements)

References 21 publications

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“…The best known of the these are based on the approach originated by Swanson, in his 'literature-based discovery', identifying linkages between the medical literature on the basis techniques for identifying and displaying terms in text and indexing, which are in common in different areas of knowledge. These methods have since been developed and since applied more widely [12].…”

Section: Information Systems and Understandingmentioning

confidence: 99%

Information and the gaining of understanding

Bawden

Robinson

2015

Journal of Information Science

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This is the accepted version of the paper.This version of the publication may differ from the final published version. Permanent repository link Information and the gaining of understanding David BawdenCentre for Information Science, City University London, United Kingdom Lyn RobinsonCentre for Information Science, City University London, United Kingdom AbstractIt is suggested that, in addition to data, information and knowledge, the information sciences should focus on understanding, understood as a higher-order knowledge, with coherent and explanatory potential. The limited ways in which understanding has been addressed in the design of information systems, in studies of information behaviour, in formulations of information literacy, and in impact studies are briefly reviewed, and future prospects considered. The paper is an extended version of a keynote presentation given at the i3 conference in June 2015.

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Section: Information Systems and Understandingmentioning

confidence: 99%

Information and the gaining of understanding

Bawden

Robinson

2015

Journal of Information Science

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“…For example, the term Raynaud Syndrome has semantic type Disease or Syndrome and Fish Oil has semantic type Lipid. We choose the same semantic types used by Weeber et al [7] and Srinivasan [10]. Thus, the semantic types for linking concepts in the present study are …”

Section: Linking Concept Selectionmentioning

confidence: 99%

Enhancing the accuracy of knowledge discovery: A supervised learning method

Cheng

Lin

Zhou

et al. 2013

2013 IEEE International Conference on Bioinformatics and Biomedicine

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Background: The amount of biomedical literature available is growing at an explosive speed, but a large amount of useful information remains undiscovered in it. Researchers can make informed biomedical hypotheses through mining this literature. Unfortunately, popular mining methods based on co-occurrence produce too many target concepts, leading to the declining relevance ranking of the potential target concepts.

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“…Most state of the art MKD systems are based on Swanson's original method Gordon and Lindsay, 1996;Pratt and Yetisgen-Yildiz, 2003;Weeber et al, 2001), some with several improvements (Hu, 2005). A limitation of MKD, however, is that it requires both the source and the target terms as input.…”

Section: Medical Knowledge Discoverymentioning

confidence: 99%

MINING THE WEB FOR MEDICAL HYPOTHESES - A Proof-of-Concept System

MacLean

Seltzer

2011

Proceedings of the International Conference on Health Informatics

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Abstract:As the prevalence of blogs, discussion forums, and online news services continues to grow, so too does the portion of this Web content that relates to health and medicine. We propose that everyday, medically-oriented Web content is a valuable and viable data source for medical hypothesis generation and testing, despite its being noisy. In this paper, we present a proof-of-concept system supporting this notion. We construct a corpus comprising news articles relating to the drugs Vioxx, Naproxen and Ibuprofen, that were published between 1998-2002. Using this corpus, we show that there was a significant link between Vioxx and the concept "Myocardial Infarction" well before the drug was withdrawn from the market in 2004. Indeed, within the Vioxx-related content, the concept ranks amongst the top 3.3% in terms of importance. When compared with the Naproxen and Ibuprofen control literatures, the term occurs significantly more frequently in the Vioxxrelated content.

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Using concepts in literature‐based discovery: Simulating Swanson's Raynaud–fish oil and migraine–magnesium discoveries

Cited by 119 publications

References 21 publications

Information and the gaining of understanding

Information and the gaining of understanding

Enhancing the accuracy of knowledge discovery: A supervised learning method

MINING THE WEB FOR MEDICAL HYPOTHESES - A Proof-of-Concept System

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