Using bovine colostrum for immunological studies

Maidment, Clem; Thomas, Julie

doi:10.1080/00219266.1995.9655425

Cited by 2 publications

(2 citation statements)

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“…Oral supplementation of vitamin E to the ewe prior to lambing may decrease lamb mortality. Four-hundred and seventy ewes were used in the first yr of a 3-yr study by Thomas et al (1995) yr (Thomas et al, 1995;Kott et al, 1998). Those lambs born to vitamin E supplemented ewes had reduced mortality rates when born in the early part of the lambing season.…”

Section: Forms and Availability Of Vitamin Ementioning

confidence: 99%

“…1995) suggested that lambs born early in the lambing season were environmentally stressed due to harsh weather conditions resulting in increased lamb mortality during this period Thomas et al (1995). showed an approximately 50 % decrease in lamb mortality in lambs born early to vitamin E supplemented ewes (first half of lambing season) compared to lambs from unsupplemented ewes (8.6 and 15.5% mortality, respectively).…”

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confidence: 99%

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Evaluation of ewe and lamb immune response when ewes were supplemented with vitamin E.

Daniels

Hatfield

Burgess

et al. 2000

Journal of Animal Science

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Fifty-two Targhee twin-bearing ewes were used in a factorial arrangement of treatments to investigate the role of supplemental vitamin E (vit E); 0 (NE) vs 400 IU of vit E x ewe x (-1)d(-1) (E) and parainfluenza type 3 (PI3) vaccination; none (NP) vs PI3 vaccination (P) in immune function. Parainfluenza type 3 vaccination was used to evoke an immune response. Ewes receiving PI3 were vaccinated at 49 and 21 d before the expected lambing date. Ewes receiving vit E were orally dosed daily, 32 to 0 d before lambing. Blood was collected from ewes at the time of the initial PI3 vaccination and 4 h postpartum. Blood was collected from lambs (n = 104) at 3 d postpartum. Ewe and lamb sera were analyzed for anti-PI3 antibody titers, immunoglobulin G (IgG) titers, and vit E concentrations. Colostrum was collected 4 h postpartum and analyzed for IgG. The model for ewe and lamb analysis included the main effects of vit E and PI3, sex (lambs model only), and their interactions. No interactions were detected (P > 0.20) for any ewe or lamb variables. Serum anti-PI3 titers were greater (P < 0.01) in P ewes and their lambs than NP ewes and their lambs. Serum vit E concentrations were greater (P < 0.01) in E ewes and their lambs than NE ewes and their lambs. Colostral IgG titers and serum anti-PI3 titers did not differ (P > 0.20) between E and NE ewes. Serum IgG titers in E ewes and their lambs did not differ (P > 0.15) from IgG titers in NE ewes and their lambs. Lamb anti-PI3 titers did not differ (P = 0.76) between lambs reared by E and NE ewes. These results indicate that, although supplemental vit E to the ewe increased lamb serum vit E concentration, it had no effect on measures used in this study to assess humoral immunity in the ewe or passive immunity to the lamb.

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Section: Forms and Availability Of Vitamin Ementioning

confidence: 99%

mentioning

confidence: 99%