Using BAMLET complex in a functional spreadable cheese elaborated with bovine colostrum

Reyes-Portillo, Karen A.; Lira, Aurora Quintero; Piloni‐Martini, Javier; Fajardo‐Espinoza, Fernanda S.; Hernández‐Sánchez, Humberto; Soto-Simental, Sergio

doi:10.1007/s13197-021-04990-0

Cited by 2 publications

(3 citation statements)

References 34 publications

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“…Due to the prevalence of innumerable bioactive constituents in BC, including immunoglobins (IgG, IgA, and IgM), lactoferrin, growth factors, and many others, upgraded technology allowed researchers to formulate innovative foods, such as cheeses, tribiotics, probiotics, ice creams, candies, and yogurts, that provide a variety of health benefits beyond basic nutritive value. Reyes-Portillo et al [ 84 ] synthesized bovine α-lactalbumin made lethal to tumor cells (BAMLET) complex from oleic acid and bovine colostrum (second and third milkings) for the development of functional cheese spread. The spread prepared from the second milking of bovine colostrum showed a yield of about 40% with high protein content, i.e., 13.56%, as compared to the spread made from the third milking.…”

Section: Bovine Colostrum As Modern Deliverable Nutraceutical Formula...mentioning

confidence: 99%

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

et al. 2022

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Bovine colostrum (BC) is the initial mammary secretion after parturition, which is nature’s bountiful source consisting of nutritional and bioactive components present in a highly concentrated low-volume format. All mammalian newborns require colostrum to enhance physiological processes such as lifelong immunity, gastrointestinal development, and resistance to microbial infections. The genetic, environmental, and processing methods can all have an impact on the biochemical contents of BC and its supplements. BC and its derivatives have been intensively researched for their potential use in functional foods, medicines, and animal feed. Evidence from clinical studies suggests that BC products are well-tolerated, nontoxic, and safe for human ingestion. Functional foods, feed, and pharmaceutical formulations based on bovine colostrum are playing noteworthy roles in the development of innovative products for promoting health and the prevention of chronic illnesses. This systematic review sheds light on recent research on (a) the effects of processing techniques on BC components, (b) emerging techniques used in the isolation and identification of novel components, (c) BC-based functional foods for human consumption and animal feed supplements, and (d) the role of BC in current drug delivery, as well as future recommendations.

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Section: Bovine Colostrum As Modern Deliverable Nutraceutical Formula...mentioning

confidence: 99%

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

et al. 2022

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“…Paclitaxel is an anti-cancer medicine frequently used in the management of lung cancer and other types of cancer at earlier and more advanced stages. Paclitaxel, derived from solvents, is an effective cancer treatment, but it is often not well tolerated and is associated with significant side effects [106]. Exosomes and other naturally occurring nanocarriers are attracting much interest as a potential way to get around these limitations.…”

Section: Targeted Oral Delivery Of Paclitaxel Through Exosomes Derive...mentioning

confidence: 99%

“…Exosomes and other naturally occurring nanocarriers are attracting much interest as a potential way to get around these limitations. According to a recent study, a tumor-targeted oral formulation of paclitaxel employing BC-derived exosomes not only enhances the clinical efficacy against orthotopic lung cancer but also reduces or eliminates the systemic and immunotoxicity of the traditional intravenous dose [106]. This finding was made possible by using exosomes derived from breast cancer cells.…”

Section: Targeted Oral Delivery Of Paclitaxel Through Exosomes Derive...mentioning

confidence: 99%

Bovine Colostrum Treatment of Specific Cancer Types: Current Evidence and Future Opportunities

et al. 2022

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Worldwide, the incidence of cancer is on the rise. Current cancer treatments include chemotherapy, radiation therapy, and surgery. Chemotherapy and radiation treatment are typically associated with severe adverse effects and a decline in patients’ quality of life. Anti-cancer substances derived from plants and animals need to be evaluated therapeutically as it is cost-effective, have fewer side effects, and can improve cancer patients’ quality of life. Recently, bovine colostrum (BC) has attracted the interest of numerous researchers investigating its anti-cancer potential in humans. Dressings loaded with BC are beneficial in treating chronic wounds and diabetic foot ulcers. Lactoferrin, a glycoprotein with potent anti-oxidant, anti-inflammatory, anti-cancer, and anti-microbial effects, is abundant in BC. The BC pills successfully promote the regression of low-grade cervical intraepithelial neoplasia when administered intravaginally. The biological, genetic, and molecular mechanisms driving BC remain to be determined. Oral BC supplements are generally well-tolerated, but some flatulence and nausea may happen. To evaluate the therapeutic effects, long-term safety, and appropriate dosages of BC drugs, well-designed clinical trials are necessary. The purpose of this article is to emphasize the anti-cancer potential of BC and its constituents.

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Using BAMLET complex in a functional spreadable cheese elaborated with bovine colostrum

Cited by 2 publications

References 34 publications

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

Bovine Colostrum Treatment of Specific Cancer Types: Current Evidence and Future Opportunities

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