Using an on-board cone-beam computed tomography scanner as an imaging modality for gel dosimetry: A feasibility study

Clinical applicability of Linac-integrated CBCT based NIPAM 3D dosimetry: a dual-institutional investigation

“…Pant demonstrated the use of CBCT based PGD in comprehensive isocenter verification within sub-mm accuracy, which is also relevant to the SRS applications (Pant et al 2020). Since all the previous studies are largely single institution research initiatives, in this study, our goal is to provide a dual-institution validation of the PGD based on Linac integrated CBCT readout (Adamson et al 2019, Shih et al 2019, Jirasek et al 2020, Pant et al 2020, Maras and Kozicki 2022. In a broader context, few multi-institutional gel studies have been accomplished previously (Kozicki et al 2020, Tachibana et al 2022.…”

“…Common PGD readout techniques include magnetic resonance imaging (MRI) (Pak et al 2013), optical computed tomography (optical CT), and x-ray CT (CT) (Hilts et al 2000, Johnston et al 2012, Maynard et al 2017. More recently linear accelerator (Linac) integrated cone-beam CT (CBCT) has been investigated (Huang et al 2010, Bong et al 2013, Shih et al 2019, Jirasek et al 2020. Despite the fact that a better contrast resolution is achieved with an MRI-readout, an accurate and clinically viable MRI dosimetry demands more technical requirements than CT and CBCT-based readout methods, (De Deene 2004, Chain et al 2011 and MRI is not as widely available thus limiting its general applicability.…”

“…Due to its spatial accuracy, CBCT-based PGD is an excellent tool in commissioning SRS and stereotactic ablative radiotherapy techniques, where there are stringent requirements for the spatial localization. Furthermore, this readout technique is available at any radiotherapy center with CBCT image guidance capability, and has the potential to be adopted widely (Adamson et al 2019, Shih et al 2019, Jirasek et al 2020, Pant et al 2020, Maras and Kozicki 2022.…”