Using ALPPS to Induce Rapid Liver Hypertrophy in a Patient with Hepatic Fibrosis and Portal Vein Thrombosis

Cavaness, Keith M.; Doyle, Majella B.; Lin, Yiing; Maynard, Erin; Chapman, William C.

doi:10.1007/s11605-012-2029-9

Cited by 35 publications

(21 citation statements)

References 8 publications

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“…Obgleich gute Erfahrungen mit diesen Parametern bei der Einschätzung der Restleberfunktion bestehen, sollte besonders bei Patienten mit großen Tumoren jedoch eine kritische Prüfung der Indikation zum "Insitu-Split" erfolgen. [16]. Im eigenen Vorgehen werden derzeit Patienten selbst mit gering ausgeprägter Leberzirrhose (CHILD A) nur im Einzelfall für einen "In-situ-Split" in Betracht gezogen.…”

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„In-situ-Split“- (ISS) Leberresektion: Neue Aspekte zu Technik und Indikation

Lang

Loss

2013

Zentralbl Chir

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The combination of right portal vein ligation with complete parenchyma dissection ("in-situ split", ISS) for rapid hypertrophy induction of the left-lateral liver lobe is a novel strategy to convert primarily irresectable liver tumours into a resectable stage. Available data so far show a 60-80 % growth induction of the remnant liver within 7(- 9) days. Certainly, a novel concept that comprises two operations within a very short time period raises questions. Based on the very few literature reports that have been published so far, as well as our own experience, we here discuss technical issues such as the use of a plastic sheet on the resection margin, the possibility of laparoscopic dissection and the timing of the second operation. Moreover, aspects of the preoperative diagnostic work-up that is necessary are assessed. Finally, open questions, e.g., concerning the influence of preoperative chemotherapy and the use of ISS in patients with cirrhosis are evaluated. In summary, the assessment of chances and risks of this novel concept with regard to indication and technical issues helps to provide the potentially curative option of the "in-situ split" procedure to more patients with marginal or even irresectable liver tumours.

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unclassified

„In-situ-Split“- (ISS) Leberresektion: Neue Aspekte zu Technik und Indikation

Lang

Loss

2013

Zentralbl Chir

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“…21 Cirrhotic patients with large tumor burdens who do not meet appropriate criteria (eg, Milan, UCSF) are not transplant candidates and therefore need an effective method for the resection and prevention of PHLF. 4 Therefore, 2-stage liver resection 12 with portal vein embolization 22 or portal vein ligation 23 has been introduced to achieve hypertrophy of the FLR. These techniques may cause problems, including delay (ranging between 3 and 8 weeks) 22,23 or the absence of hypertrophy.…”

Section: Resultsmentioning

confidence: 99%

Totally Laparoscopic Associating Liver Tourniquet and Portal Ligation for Staged Hepatectomy via Anterior Approach for Cirrhotic Hepatocellular Carcinoma

Zhang

Yang

Chen

et al. 2015

Journal of the American College of Surgeons

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“…Luego de una mediana de intervalo de 9 días, la mediana de volumen del lóbulo izquierdo fue de 536 cc, con un delta de volumen de 225 cc, y un incremento de volumen de 74% 3 . numerosos artículos y comentarios han sido posteriormente publicados al respecto 6,[16][17][18][19][20][21] .…”

Section: Discussionunclassified

“…En este caso el rol de la bipartición es evidente, ya que no se produjo hipertrofia del lóbulo izquierdo cuando sólo se ligó la vena porta derecha. Los resultados obtenidos a corto plazo en nuestra paciente son similares a los reportados en la literatura existente 6,[16][17][18][19][20][21] .…”

Section: Discussionunclassified

Asociación De La Partición Hepática Y Ligadura De La Vena Portal Para Hepatectomía Por Etapas, Un Nuevo Procedimiento en Cirugía Hepática

Núñez

et al. 2015

Rev Chil Cir

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associating liver partition and portal vein ligation for staged hepatectomy, a new hepatic procedure introduction: Hepatic resection is the standard treatment for the liver tumors and in most cases the only potentially curative option. The most feared complication, in the major hepatic resection, is the postoperative liver failure. A new technique has recently been published in the literature: Liver partition associated to a portal vein ligation for staged hepatectomy. This technique allows an accelerated hipertrophy of the remnant liver, facilitates greater resection surgery, reducing the risk of postoperative hepatic ischemia. The results reported in the literature are promising. We report the first case in Chile with its evolution to 2 years and a discussion about the topic.

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Using ALPPS to Induce Rapid Liver Hypertrophy in a Patient with Hepatic Fibrosis and Portal Vein Thrombosis

Cited by 35 publications

References 8 publications

„In-situ-Split“- (ISS) Leberresektion: Neue Aspekte zu Technik und Indikation

„In-situ-Split“- (ISS) Leberresektion: Neue Aspekte zu Technik und Indikation

Totally Laparoscopic Associating Liver Tourniquet and Portal Ligation for Staged Hepatectomy via Anterior Approach for Cirrhotic Hepatocellular Carcinoma

Asociación De La Partición Hepática Y Ligadura De La Vena Portal Para Hepatectomía Por Etapas, Un Nuevo Procedimiento en Cirugía Hepática

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