Using a low-cost, real-time electronic immunization registry in Pakistan to demonstrate utility of data for immunization programs and evidence-based decision making to achieve SDG-3: Insights from analysis of Big Data on vaccines

Siddiqi, Danya Arif; Abdullah, Sara; Dharma, Vijay Kumar; Shah, Mubarak Taighoon; Akhter, Mohammed Adil; Habib, Ali; Khan, Aamir; Chandir, Subhash

doi:10.1016/j.ijmedinf.2021.104413

Cited by 18 publications

(16 citation statements)

References 6 publications

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“…A study conducted among low-income countries to assess the performance of electronic vaccine registries describes some of the benefits brought about by the ability of the systems to perform their functions, including offering numerous opportunities to increase the timeliness, accuracy, and particularity of performance measures [17] which is similar to what the Chanjotrack system offered. Another function that has been exhibited by the Chanjotrack system that is similar to other electronic vaccine registries is that of ensuring access to big vaccines data and helping generate meaningful insights to drive actions and data-driven decisions [18].…”

Section: Discussionmentioning

confidence: 99%

User Acceptability of Electronic Vaccine Registry Created using Simple Mobile Phone Technology in Nyandarua County, Kenya

Juma¹

2022

TIJPH

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Vaccination is one of the most important and effective public health interventions against vaccine-preventable diseases. Developed countries have successfully reduced mortality and morbidity due to vaccine-preventable diseases through improving vaccine coverage. This is not the case among low-income countries as vaccine coverages continue to soar below the global target of 90% coverage. Among the reasons reported for the low coverage are poor documentation and poor target setting, which could be attributed to the limited use of electronic vaccine registries. An electronic vaccine registry was created using Unstructured Supplementary Service Data (USSD) technology and registered births, vaccines administered, and sent short message reminders to mothers about their clinic dates. The registry was deployed in Nyandarua County, Kenya, between June 2018 to March 2019. We conducted a study to establish the acceptability and usability of the system to receive user feedback and explore possibilities of large-scale roll-out. All those interviewed (59) were able to log into the system during their first attempt. The majority (94.8%) reported that it was easy to manoeuvre the menu and move from one menu to the other System downtime was a rare phenomenon, and more than half (63%) reported that if it occurred, it happened at most once or twice per week. The majority of the respondents, 55 (98%), reported that the system was able to record the vaccines administered as envisioned. The cost to run the platform was quite manageable and slightly lower than internet-based systems. The system was user-friendly and can be replicated elsewhere.

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Section: Discussionmentioning

confidence: 99%

User Acceptability of Electronic Vaccine Registry Created using Simple Mobile Phone Technology in Nyandarua County, Kenya

Juma¹

2022

TIJPH

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“…Poor uptake of routine childhood immunisations as per official records from the Government of Sindh’s electronic immunisation registry—where Districts Korangi, South and East had a median vaccination rate of 33.2%, 40.6% and 39.1%, respectively, of children born in 2020 25 (recommended is >85%). Routine childhood immunisation served as a proxy for COVID-19 immunisation rates, as COVID-19 vaccination data were not available at the district level.…”

Section: Methodsmentioning

confidence: 99%

Jeelo Dobara (Live Life Again): a cross-sectional survey to understand the use of social media and community experience and perceptions around COVID-19 vaccine uptake in three low vaccine uptake districts in Karachi, Pakistan

et al. 2023

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ObjectiveTo gather preliminary insights through formative research on social media usage, and experiences, attitudes and perceptions around COVID-19 and COVID-19 vaccination in three high-risk, underserved districts in Karachi, Pakistan.DesignCross-sectional mixed-method design.Participants392 adults (361 surveys and 30 in-depth interviews (IDI)) from districts South, East and Korangi in Karachi, Pakistan.Main outcome measuresSocial media usage and knowledge, perception and behaviour towards COVID-19 infection and vaccination.ResultsUsing social media was associated with an increased probability of getting vaccinated by 1.61 units. Most of the respondents (65%) reported using social media, mainly to watch videos and/or keep in touch with family/friends. 84.76% knew of COVID-19 while 88.37% knew about the COVID-19 vaccination, with 71.19% reported vaccine receipt; reasons to vaccinate included belief that vaccines protect from the virus, and vaccination being mandatory for work. However, only 56.7% of respondents believed they were at risk of disease. Of the 54 unvaccinated individuals, 27.78% did not vaccinate as they did not believe in COVID-19. Despite this, 78.38% of respondents scored high on vaccine confidence. In IDIs, most respondents knew about COVID-19 vaccines: ‘This vaccine will create immunity in your body. Therefore, I think we should get vaccinated’, and over half knew how COVID-19 spreads. Most considered COVID-19 a serious public health problem and thought it important that people get vaccinated. However, there was a low-risk perception of self as only a little over half felt that they were at risk of contracting COVID-19.ConclusionWith our conflicting results regarding COVID-19 vaccine confidence, that is, high vaccine coverage but low perception of risk to self, it is likely that vaccine coverage is more a result of mandates and coercion than true vaccine confidence. Our findings imply that interactive social media could be valuable in fostering provaccine sentiment.

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“…Studies that use currently available real‐world big data are carried out under low financial burden, and long‐term observation is possible. 21 Large‐scale observational studies using real‐world big data can complement the evidence gap left unfilled by RCTs. 22 , 23 Many studies undertaken outside of Japan that use big data have been reported even in critical care fields.…”

Section: Difference In Strength Between Real‐world Evidence and Rctsmentioning

confidence: 99%

“…The difference between RCTs and real‐world clinical studies using DPC big data is summarized in Table 4. Studies that use currently available real‐world big data are carried out under low financial burden, and long‐term observation is possible 21 . Large‐scale observational studies using real‐world big data can complement the evidence gap left unfilled by RCTs 22,23 .…”

Section: Difference In Strength Between Real‐world Evidence and Rctsmentioning

confidence: 99%

Real‐world evidence on disseminated intravascular coagulation from Japan

Hisamune

Mochizuki

2023

Acute Medicine & Surgery

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Many descriptive epidemiological and comparative studies using big data have been reported recently from outside Japan. Within Japan, diagnosis procedure combination (DPC) data and medical receipt data are being stored in electronic media, and real‐world evidence in various fields has started to be reported. We reviewed clinical studies on disseminated intravascular coagulation (DIC) using DPC data obtained from an insurance database with large numbers of cases and a related commercially available dataset including DPC and laboratory data. After DPC was introduced in 2003, 19 studies on DIC using Japanese national DPC data and two studies using the Medical Data Vision database were reported. Epidemiological findings in seven studies showed that the proportion of drugs administered for each underlying disease differed, with antithrombin and recombinant thrombomodulin (rTM) being used more frequently in clinical settings. In 14 comparative studies on anti‐DIC agents, antithrombin for severe pneumonia, postoperative intestinal perforation, and severe burn, and rTM for acute cholangitis were associated with improved survival rates. Large‐scale observational studies using big data can show results similar to those of randomized control trials if the quality of individual research is high. Real‐world data analysis will be increasingly necessary to complement the evidence gap unfilled by randomized control trials.

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Using a low-cost, real-time electronic immunization registry in Pakistan to demonstrate utility of data for immunization programs and evidence-based decision making to achieve SDG-3: Insights from analysis of Big Data on vaccines

Cited by 18 publications

References 6 publications

User Acceptability of Electronic Vaccine Registry Created using Simple Mobile Phone Technology in Nyandarua County, Kenya

User Acceptability of Electronic Vaccine Registry Created using Simple Mobile Phone Technology in Nyandarua County, Kenya

Jeelo Dobara (Live Life Again): a cross-sectional survey to understand the use of social media and community experience and perceptions around COVID-19 vaccine uptake in three low vaccine uptake districts in Karachi, Pakistan

Real‐world evidence on disseminated intravascular coagulation from Japan

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