Using a deep neural network for four-dimensional CT artifact reduction in image-guided radiotherapy

Mori, Shinichiro; Hirai, Ryusuke; Sakata, Yoshihito

doi:10.1016/j.ejmp.2019.08.008

Cited by 10 publications

(14 citation statements)

References 29 publications

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“…After 5 minutes, massage was used to induce penile erection, and its length and circumference were measured. en, the Doppler ultrasound was used to detect bilateral deep penile arteries, peak systolic velocity (PSV), peak end-diastolic velocity, and blood flow resistance index (RI) [2,3].…”

Section: Operation Methodmentioning

confidence: 99%

Application and Value of Dynamic Volume CT Multiparameter Imaging in the Diagnosis of Traumatic High-Flow Penile Abnormal Erection

Ruan

Pan

et al. 2021

Scientific Programming

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Objective. To explore the clinical application of dynamic volume CT multiparameter imaging in the observation of penile hemodynamics in patients with abnormal vascular erections. Methods. 90 patients with suspected vascular abnormal erections treated in our hospital from January 2016 to January 2020 were included in the study, and 40 patients with psychologically abnormal erections were selected for the control. The corpus cavernosum injection vasoactive drug test (ICI) and dynamic volume CT and Doppler ultrasound were used to test the hemodynamics of the corpus cavernosum of all selected patients and to analyze the changes of penile length, circumference, systolic peak flow rate, diastolic peak flow rate, and blood flow resistance index in different types of penile erection disorder patients before and after ICI test. Results. Among the 90 patients with suspected vascular abnormal erection, 34 patients had arterial abnormal erection, 25 patients had venous abnormal erection, and 31 patients had mixed vascular abnormal erection. In patients with arterial abnormal erection and mixed vascular abnormal erection, penile cavernous body diameter, PSV, and abnormal erection V are smaller than those in patients with venous abnormal erection and psychological abnormal erection, while arterial abnormal erection and psychological abnormal erection are obviously higher in RI than venous abnormal erection and mixed vascular abnormal erection, and the difference is statistically significant ( P < 0.05 ). Before the ICI test, there was no significant difference in the penis circumference and length between the four groups of patients with arterial abnormal erection, venous abnormal erection, mixed vascular abnormal erection, and psychological abnormal erection ( P > 0.05 ); after the ICI test, patients with arterial abnormal erections had significantly shorter penis perimeter and penis length than those with venous abnormal erections, mixed vascular abnormal erections, and psychological abnormal erections ( P < 0.05 ). Conclusion. Dynamic volume CT can clearly reflect the penile hemodynamic state of patients with vascular abnormal erections, provide a powerful diagnostic basis for accurately and effectively determining the classification of vascular abnormal erections, and be worthy of popularization and clinical use.

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Section: Operation Methodmentioning

confidence: 99%

Application and Value of Dynamic Volume CT Multiparameter Imaging in the Diagnosis of Traumatic High-Flow Penile Abnormal Erection

Ruan

Pan

et al. 2021

Scientific Programming

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“…For a small tumor, the internal respiratory measured CT produced a smaller volume than that from the CT image obtained using external surrogates. Recently, machine learning using deep neural network approaches are being investigated to reduce the magnitude of 4D-CT artifacts [44].…”

Section: Motion Incorporated Imagingmentioning

confidence: 99%

Current status of proton therapy techniques for lung cancer

Han

2019

Radiat Oncol J

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Proton beams have been used for cancer treatment for more than 28 years, and several technological advancements have been made to achieve improved clinical outcomes by delivering more accurate and conformal doses to the target cancer cells while minimizing the dose to normal tissues. The state-of-the-art intensity modulated proton therapy is now prevailing as a major treatment technique in proton facilities worldwide, but still faces many challenges in being applied to the lung. Thus, in this article, the current status of proton therapy technique is reviewed and issues regarding the relevant uncertainty in proton therapy in the lung are summarized.

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“…CT and CBCT or CT and magnetic resonance images (MRI)) and preserve the anatomy of the daily images in the derived synthetic CT images (sCT). Several studies achieved a significant artifacts reduction and therefore increased the potential for a clinical implementation of ART for different anatomical regions [20][21][22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a cycle-generative adversarial network-based cone-beam CT to synthetic CT conversion algorithm for adaptive radiation therapy

et al. 2020

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Image-guided radiation therapy could benefit from implementing adaptive radiation therapy (ART) techniques. A cycle-generative adversarial network (cycle-GAN)-based cone-beam computed tomography (CBCT)-to-synthetic CT (sCT) conversion algorithm was evaluated regarding image quality, image segmentation and dosimetric accuracy for head and neck (H&N), thoracic and pelvic body regions. Methods: Using a cycle-GAN, three body site-specific models were priorly trained with independent paired CT and CBCT datasets of a kV imaging system (XVI, Elekta). sCT were generated based on first-fraction CBCT for 15 patients of each body region. Mean errors (ME) and mean absolute errors (MAE) were analyzed for the sCT. On the sCT, manually delineated structures were compared to deformed structures from the planning CT (pCT) and evaluated with standard segmentation metrics. Treatment plans were recalculated on sCT. A comparison of clinically relevant dose-volume parameters (D 98 , D 50 and D 2 of the target volume) and 3D-gamma (3%/3mm) analysis were performed. Results: The mean ME and MAE were 1.4, 29.6, 5.4 Hounsfield units (HU) and 77.2, 94.2, 41.8 HU for H&N, thoracic and pelvic region, respectively. Dice similarity coefficients varied between 66.7 ± 8.3% (seminal vesicles) and 94.9 ± 2.0% (lungs). Maximum mean surface distances were 6.3 mm (heart), followed by 3.5 mm (brainstem). The mean dosimetric differences of the target volumes did not exceed 1.7%. Mean 3D gamma pass rates greater than 97.8% were achieved in all cases. Conclusions: The presented method generates sCT images with a quality close to pCT and yielded clinically acceptable dosimetric deviations. Thus, an important prerequisite towards clinical implementation of CBCTbased ART is fulfilled.

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Using a deep neural network for four-dimensional CT artifact reduction in image-guided radiotherapy

Cited by 10 publications

References 29 publications

Application and Value of Dynamic Volume CT Multiparameter Imaging in the Diagnosis of Traumatic High-Flow Penile Abnormal Erection

Application and Value of Dynamic Volume CT Multiparameter Imaging in the Diagnosis of Traumatic High-Flow Penile Abnormal Erection

Current status of proton therapy techniques for lung cancer

Evaluation of a cycle-generative adversarial network-based cone-beam CT to synthetic CT conversion algorithm for adaptive radiation therapy

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