Usefulness of the Global Leadership Initiative on Malnutrition criteria to predict sarcopenia and mortality in patients with chronic liver disease

Miwa, Takao; Hanai, Taizo; Nishimura, Kayoko; Unome, Shinji; Maeda, Takeshi; Ogiso, Yui; Imai, Kenji; Suetsugu, Atsushi; Koji, Takehiko; Shimizu, Masahito

doi:10.1111/hepr.13816

Cited by 21 publications

(25 citation statements)

References 45 publications

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“…Among the 174 non-tumor patients, the prevalence was 9.77, 10.92, and 32.18% as determined by the GLIM, SGA, and PNI, respectively. A similar conclusion was reached by Miwa' study ( 22 ), the GLIM also showed the lowest prevalence (21%) among chronic liver disease patients when compared with SGA(35%), and RFH-GA (26%). As we know, the incidence of malnutrition varies relay on how estimator used the assessment tools, but regardless of the assessment tool, clinical outcomes in hospitalized patients with or without malnutrition are quite different.…”

Section: Discussionsupporting

confidence: 83%

Comparison of GLIM, SGA, PG-SGA, and PNI in diagnosing malnutrition among hepatobiliary-pancreatic surgery patients

Zhou

Ding

et al. 2023

Front. Nutr.

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ObjectiveTo compare the diagnostic value of four tools—the Global Leadership Initiative on Malnutrition (GLIM) criteria, the subjective global assessment (SGA), patient-generated subjective global assessment (PG-SGA), and prognostic nutritional index (PNI) in malnutrition among hospitalized patients undergoing hepatobiliary-pancreatic surgery. Meanwhile, to observe the nutritional intervention of these patients.MethodsPresent study was a cross-sectional study, including 506 hospitalized patients who underwent hepatobiliary-pancreatic surgery between December 2020 and February 2022 at Ningbo Medical Center Lihuili Hospital, China. The incidence rate of malnutrition was diagnosed using the four tools. The consistency of the four tools was analyzed by Cohen's kappa statistic. Data, including nutritional characteristics and nutritional interventions, were collected. The nutritional intervention was observed according to the principles of Five Steps Nutritional Treatment.ResultsThe prevalence was 36.75, 44.58, and 60.24%, as diagnosed by the GLIM, PG-SGA, and PNI, respectively, among 332 tumor patients. Among the 174 non-tumor patients, the prevalence was 9.77, 10.92, and 32.18% as diagnosed by the GLIM, SGA, and PNI. The diagnostic concordance of PG-SGA and GLIM was higher (Kappa = 0.814, <0.001) than SGA vs. GLIM (Kappa = 0.752, P < 0.001) and PNI vs. GLIM (Kappa = 0.265, P < 0.001). The univariate analysis revealed that older age, lower BMI and tumorous were significantly associated with nutritional risks and malnutrition. Among 170 patients with nutritional risk, most of patients (118/170, 69.41%) did not meet the nutritional support standard.ConclusionThe incidence of nutritional risk and malnutrition is high among patients with hepatobiliary and pancreatic diseases, specifically those with tumors. The GLIM showed the lowest prevalence of malnutrition among the four tools. The PG-SGA and GLIM had a relative high level of agreement. There was a low proportion of nutritional support in patients. More prospective and well-designed cohort studies are needed to confirm the relevance of these criteria in clinical practice in the future.

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Section: Discussionsupporting

confidence: 83%

Comparison of GLIM, SGA, PG-SGA, and PNI in diagnosing malnutrition among hepatobiliary-pancreatic surgery patients

Zhou

Ding

et al. 2023

Front. Nutr.

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“…The odds ratio (OR) for concurrent complicating sarcopenia was between 2 and 3 for the three nutritional constructs. Adjusted hazard ratios were significant for 1-year mortality by GLIM (1.95) and SGA (1.57), but not for RFH-GA [16 ▪ ].…”

Section: Resultsmentioning

confidence: 86%

Validity and feasibility of the global leadership initiative on malnutrition diagnostic concept in older people: a literature review from August 2021 to August 2022

Cederholm

Barazzoni

2022

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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Purpose of reviewEarly 2019, the Global Leadership Initiative on Malnutrition (GLIM) concept offered a clinically applicable and objective procedure for diagnosing malnutrition. This review summarizes 40 publications from August 2021 to August 2022 that applied the GLIM criteria in older populations from various clinical settings for criterion and predictive validation. Recent findingsCriterion validity studies, by comparing the GLIM construct with various semi-gold standards such as SGA, PG-SGA, MNA-FF/SF and ESPEN criteria, indicate by sensitivity, specificity and agreement that GLIM performs at least as well as the other tools to capture malnutrition. One meta-analysis of 20 studies with various comparators reports high accuracy for distinguishing malnutrition. GLIM-malnutrition prevalence figures vary with screening tool. Predictive validity of GLIM for mortality, and other outcomes, is good in all settings reported. Sarcopenia and GLIM show some expected overlapping.

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“…GLIM is a two-step model for risk screening and diagnostic assessment. Since its introduction, the GLIM has been validated in a variety of diseases, including cancer, chronic liver disease, chronic kidney disease, and heart failure (11)(12)(13)(14).…”

Section: Introductionmentioning

confidence: 99%

The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients

et al. 2022

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BackgroundThis study aimed to investigate the value of the Geriatric Nutritional Risk Index (GNRI), prognostic nutritional index (PNI), and advanced lung cancer inflammation index (ALI) scores in detecting malnutrition in patients with rectal cancer; the Global Leadership Initiative on Malnutrition (GLIM) was used as the reference criterion.Materials and methodsThis study included patients with rectal cancer who underwent proctectomy. GNRI, PNI, and ALI were calculated to detect the GLIM-defined malnutrition using the Receiver operating characteristic (ROC) curves. Univariate and multivariate logistic regression analyses were used to evaluate the association between the nutritional tools and postoperative complications. Kaplan-Meier survival curves, log-rank tests, and univariate and multivariate Cox regression analyses were used to clarify the relationship between nutritional tools and overall survival (OS).ResultsThis study enrolled 636 patients with rectal cancer. The GNRI demonstrated the highest sensitivity (77.8%), pretty specificity (69.0%), and the largest AUC (0.734). The GNRI showed good property in predicting major postoperative complications. All three nutritional tools were independent predictors of OS.ConclusionThe GNRI can be used as a promising alternative to the GLIM and is optimal in perioperative management of patients with rectal cancer.

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Usefulness of the Global Leadership Initiative on Malnutrition criteria to predict sarcopenia and mortality in patients with chronic liver disease

Cited by 21 publications

References 45 publications

Comparison of GLIM, SGA, PG-SGA, and PNI in diagnosing malnutrition among hepatobiliary-pancreatic surgery patients

Comparison of GLIM, SGA, PG-SGA, and PNI in diagnosing malnutrition among hepatobiliary-pancreatic surgery patients

Validity and feasibility of the global leadership initiative on malnutrition diagnostic concept in older people: a literature review from August 2021 to August 2022

The geriatric nutritional risk index is an effective tool to detect GLIM-defined malnutrition in rectal cancer patients

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