“…Since, several thousand articles have been published about speckle tracking echocardiography (STE), with increasing impact on clinical management of patients in cardiology. In these studies, typical patterns of differing segmental strain curves in the left ventricle have been described for the assessment of acute and chronic ischemic heart disease (Stoylen, et al 2000, Hanekom, et al 2005, Miyasaka, et al 2005, Grenne, et al 2010, different forms of ventricular hypertrophy (Cikes, et al 2010), storage diseases (Phelan, et al 2012), cardiomyopathies (Haugaa, et al 2012), transplant rejection (Marciniak, et al 2007), cardiac dyssynchrony (Parsai, et al 2009) congenital heart disease (Friedberg and Mertens 2009) and risk evaluation for cardiac arrhythmias (Haugaa, et al 2012) to name a few. At present, two-dimensional (2D) STE is implemented on most ultrasound systems and has become the most frequently used tool for non-invasive assessment of regional myocardial function.…”