Abstract:Chronic refractory angina pectoris (AP) affects 600,000 to 1,800,000 Americans, with approximately 50,000 new cases annually. A recent study revealed long-term mortality of refractory AP to be lower than previously reported, with >70% of patients living >9 years. Treating AP can improve quality of life. We describe a patient with refractory AP who underwent a successful stellate ganglion block for symptom control.
“…The conservative treatment included administration of medications, such as nonsteroidal anti-inflammatory drugs, COX-2 inhibitor, tramadol, acetaminophen, physical therapy, and soft collar immobilization. Patients with recurrent sympathetic symptoms received stellate ganglion blocks using the paravertebral technique, as described in previous studies 19–21…”
Section: Methodsmentioning
confidence: 99%
“…Patients with recurrent sympathetic symptoms received stellate ganglion blocks using the paravertebral technique, as described in previous studies. [19][20][21]…”
Objective: This retrospective cohort study aimed to compare the outcomes of anterior cervical discectomy and fusion (ACDF), and those of conservative treatment for patients with cervical angina.Summary of Background Data: Cervical angina is typically characterized by intolerable and paroxysmal angina-like precordial pain, which is caused by cervical disk degeneration in patients without definitive cardiovascular abnormalities. Diagnosis is either delayed or neglected because of its various clinical manifestations. Whether conservative or surgical treatment is appropriate remains controversial because of the lack of comparative studies.Materials and Methods: From 2009 to 2016, 163 patients with cervical angina with advanced chest pain, tightness, or palpitation were retrospectively studied. Twenty-three patients underwent ACDF, and the other 140 patients were treated nonsurgically by medication, physical therapy, collar immobilization, or stellate ganglion block. Japanese Orthopedic Association (JOA) score and 20-point autonomic nervous system (ANS) score were assessed pretreatment and posttreatment. Patients' satisfaction was assessed using the Odom criteria.
Results:The average age of the patients was 50 years, and most of them were females. The average follow-up was 25.5 months. The pretreatment JOA and 20-point ANS scores in the conservative and ACDF groups were 13.3 versus 11.7 (P = 0.110) and 13.0 versus 13.3 (P = 0.928), respectively. Generalized esti-mating equation analysis showed that posttreatment JOA and ANS scores at each observation interval improved significantly in the ACDF group (P < 0.001). Angina-like symptoms also improved significantly in the ACDF group (P < 0.001). During an average 2-year follow-up, good or excellent results were obtained in 78.2% of surgical patients and 35% of nonsurgical patients.Conclusions: Compared with conservative therapy, surgical treatment with ACDF for cervical angina provided better and more consistent relief from angina-like symptoms and overall sympathetic symptoms.
“…The conservative treatment included administration of medications, such as nonsteroidal anti-inflammatory drugs, COX-2 inhibitor, tramadol, acetaminophen, physical therapy, and soft collar immobilization. Patients with recurrent sympathetic symptoms received stellate ganglion blocks using the paravertebral technique, as described in previous studies 19–21…”
Section: Methodsmentioning
confidence: 99%
“…Patients with recurrent sympathetic symptoms received stellate ganglion blocks using the paravertebral technique, as described in previous studies. [19][20][21]…”
Objective: This retrospective cohort study aimed to compare the outcomes of anterior cervical discectomy and fusion (ACDF), and those of conservative treatment for patients with cervical angina.Summary of Background Data: Cervical angina is typically characterized by intolerable and paroxysmal angina-like precordial pain, which is caused by cervical disk degeneration in patients without definitive cardiovascular abnormalities. Diagnosis is either delayed or neglected because of its various clinical manifestations. Whether conservative or surgical treatment is appropriate remains controversial because of the lack of comparative studies.Materials and Methods: From 2009 to 2016, 163 patients with cervical angina with advanced chest pain, tightness, or palpitation were retrospectively studied. Twenty-three patients underwent ACDF, and the other 140 patients were treated nonsurgically by medication, physical therapy, collar immobilization, or stellate ganglion block. Japanese Orthopedic Association (JOA) score and 20-point autonomic nervous system (ANS) score were assessed pretreatment and posttreatment. Patients' satisfaction was assessed using the Odom criteria.
Results:The average age of the patients was 50 years, and most of them were females. The average follow-up was 25.5 months. The pretreatment JOA and 20-point ANS scores in the conservative and ACDF groups were 13.3 versus 11.7 (P = 0.110) and 13.0 versus 13.3 (P = 0.928), respectively. Generalized esti-mating equation analysis showed that posttreatment JOA and ANS scores at each observation interval improved significantly in the ACDF group (P < 0.001). Angina-like symptoms also improved significantly in the ACDF group (P < 0.001). During an average 2-year follow-up, good or excellent results were obtained in 78.2% of surgical patients and 35% of nonsurgical patients.Conclusions: Compared with conservative therapy, surgical treatment with ACDF for cervical angina provided better and more consistent relief from angina-like symptoms and overall sympathetic symptoms.
“…6 SGB has a wide range of indications, including the management of complex regional pain syndrome (type I and II), hot flashes, sleep disturbance, angina, electric storm, long Q-T syndrome, ventricular tachycardia, diabetes, essential hypertension and postoperative cognitive dysfunction. [7][8][9][10] Previous studies have shown that preoperative SGB facilitates haemodynamic stabilisation during the process of anaesthesia induction, endotracheal intubation and pneumoperitoneum, and provide the beneficial effect of myocardial injury and preventing adverse cardiovascular events in high-risk patients. 11 12 Other researchers have found that SGB reduces postoperative pain,…”
IntroductionStellate ganglion block (SGB) is usually used in the department of algiatry. But preoperative SGB may reduce adverse cardiovascular events in high-risk patients, although evidence remains sparse. Therefore, we aim to determine whether a single-shot postoperative SGB can reduce the incidence of myocardial injury after non-cardiac surgery (MINS) and improve recovery in patients undergoing laparoscopic radical resection for colorectal cancer.Methods and analysisThis is an investigator-initiated, single-centre, randomised, two-arm clinical trial enrolling patients aged over 45 years and scheduled for elective laparoscopic radical colorectal surgery with at least one risk factor for MINS. A total of 950 eligible patients will be randomised into a routine or block groups. The primary outcome is the incidence of MINS. The secondary outcomes include the Visual Analogue Scale of pain during rest and movement, the incidence of delirium, quality of recovery (QOR) assessed by QOR-15, and sleep quality assessed by Richards Campbell Sleep Questionnaire. Tertiary outcomes include time to first flatus, gastrointestinal complications such as anastomotic leak or ileus, length of hospital stay, collapse incidence of severe cardiovascular and cerebrovascular complications of myocardial infarction, cardiac arrest, ischaemic or haemorrhagic stroke, and all-cause mortality within 30 days after the operation.Ethics and disseminationThe protocol was approved by Medical Ethics Committee of the China-Japan Union Hospital, Jilin University (Approval number: 2021081018) prior to recruitment. The study will be performed according to the guidelines of the Declaration of Helsinki. The findings of this study will be published and presented through various scientific forums.Trial registration numberChiCTR2200055319.
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