Usefulness of quantitative intravenous myocardial contrast echocardiography to analyze microvasculature perfusion in patients with a recent myocardial infarction and an open infarct-related artery: comparison with intracoronary myocardial contrast echocardiography

Abstract

Intravenous contrast echocardiography is a useful technique to analyze microvasculature perfusion soon after infarction. A quantitative analysis of single-triggered images is an easy-to-obtain and reliable method to define perfusion when compared with intracoronary contrast echocardiography.

Microvascular perfusion 1 week and 6 months after myocardial infarction by first-pass perfusion cardiovascular magnetic resonance imaging

“…1 In patients with an open infarct-related artery (IRA), a lack of perfusion at the microvascular level is related to worse outcome. [1][2][3][4][5] The extent of abnormal perfusion may change in the months after myocardial infarction. 5 6 Cardiovascular magnetic resonance imaging (CMR) allows state-of-the-art analysis of the heart in different clinical scenarios.…”

Microvascular Obstruction Remains a Portent of Adverse Remodeling in Optimally Treated Patients With Left Ventricular Systolic Dysfunction After Acute Myocardial Infarction

“…Despite patency of the IRA, however, abnormal microvascular perfusion-termed microvascular obstruction (MO)-is related to worse outcome. 1,2 Cardiac MRI (CMR) facilitates examination of myocardial perfusion through early and delayed contrast-enhanced imaging sequences (ceCMR). Analysis of myocardial enhancement early (usually 2 to 5 minutes) after injection of a gadolinium-based contrast agent allows visualization of "early MO," an area of hypoenhanced myocardium that bears a precise anatomic correlation with markedly reduced blood flow in animal studies, in addition to biopsy evidence of necrotic debris.…”

Microvascular damage prevention with thrombaspiration during primary percutaneous intervention in acute myocardial infarction

“…In Galiuto et al's [23] publication, myocardial perfusion was also evaluated by contrast echocardiography. Nevertheless, only in our study quantitative analysis that enables more precise assessment of myocardium viability was used [24]. Objective QMCE includes evaluation of maximal contrast intensity in myocardium, myocardium filling rate and enables prompt interpretation of myocardial perfusion.…”