Abstract:Background: Paraoxonase 1 (PON1) is closely associated with the antioxidant, anti-inflammatory, and antiatherosclerotic functions of HDL. Although many clinical studies have evaluated the relationship between PON1 activity and various diseases, there are inconsistencies in sample preparation methods and substrate selection for PON1 analysis. Moreover, depending on the selected substrates, various types of PON1 activities can be measured, which would be an obstacle of dissemination of clinical practice. Here, w… Show more
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