Usefulness of intracranial EEG in the decision process for epilepsy surgery

Pondal‐Sordo, Margarita; Diosy, David; Téllez‐Zenteno, José F.; Sahjpaul, Ramesh; Wiebe, Samuel

doi:10.1016/j.eplepsyres.2007.03.011

Cited by 50 publications

(34 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This identification is done by a visual inspection of the EEG data by clinicians, which is a difficult and time consuming task. For a better spatial resolution (in particular if EEG is insufficient for the localization) an invasive recording using subdural strip electrodes (electrocorticography, ECoG), which are placed directly on the brain surface, is performed (see Pondal-Sordo et al, 2007). …”

Section: Methodsmentioning

confidence: 99%

Influence analysis for high-dimensional time series with an application to epileptic seizure onset zone detection

Flamm

Graef

Pirker

et al. 2013

Journal of Neuroscience Methods

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

Influence analysis for high-dimensional time series with an application to epileptic seizure onset zone detection

Flamm

Graef

Pirker

et al. 2013

Journal of Neuroscience Methods

View full text Add to dashboard Cite

show abstract

“…They have instead been used as supplementary tools to determine the locations of intracranial EEG (iEEG) electrodes because of their limited spatial resolution. Indeed, in modern clinical neurophysiology, iEEG recorded from subdural electrodes is regarded as the most reliable modality for determining surgical resection areas prior to epilepsy surgery (Binnie et al 1994;Behrens et al 1994;Dubeau and McLachlan 2000;Rosenow and Lüders 2001;Pondal-Sordo et al 2007).…”

mentioning

confidence: 99%

Evaluation of Algorithms for Intracranial EEG (iEEG) Source Imaging of Extended Sources: Feasibility of Using iEEG Source Imaging for Localizing Epileptogenic Zones in Secondary Generalized Epilepsy

et al. 2011

View full text Add to dashboard Cite

Precise identification of epileptogenic zones in patients with intractable drug-resistant epilepsy is critical for successful epilepsy surgery. Numerous source-imaging algorithms for localizing epileptogenic zones based on scalp electroencephalography (EEG) and magnetoencephalography (MEG) have been developed and validated in simulation and experimental studies. Recently, intracranial EEG (iEEG)-based imaging of epileptogenic sources has attracted interest as a promising tool for presurgical evaluation of epilepsy; however, most iEEG studies have focused on localization of epileptogenic zones in focal epilepsy. In the present study, we investigated whether iEEG source imaging is a useful supplementary tool for identifying extended epileptogenic sources in secondary generalized epilepsy such as Lennox-Gastaut syndrome (LGS). To this end, we applied four different cortical source imaging algorithms, namely minimum norm estimation (MNE), low-resolution electromagnetic tomography (LORETA), standardized LORETA (sLORETA), and L(p)-norm estimation (p = 1.5, referred to as Lp1.5), to artificial iEEG datasets generated assuming various source sizes and locations. We also applied these four algorithms to clinical ictal iEEG recordings acquired from a pediatric patient with LGS. Interestingly, the traditional MNE algorithm outperformed the other imaging algorithms in most of our experiments, particularly in cases when larger-sized sources were activated. Although sLORETA outperformed both LORETA and Lp1.5, its performance was not as good as that of MNE. Compared to the other algorithms, the performance of Lp1.5 decayed most rapidly as the source size increased. Our findings suggest that iEEG source imaging using MNE is a promising auxiliary tool for the identification of epileptogenic zones in secondary generalized epilepsy. We anticipate that our results will provide useful guidelines for selection of an appropriate imaging algorithm for iEEG source imaging studies.

show abstract

“…Seizures that are localizable on EEG are significantly more likely to resolve with surgical resection (19,20). The utilization of intracranial electrode recording expands the diagnostic capabilities of EEG with improved spatial and temporal resolution of ictal recordings (21), especially in cases where scalp recordings are either nondiagnostic or incongruous with clinical and radiographic findings.…”

Section: Preoperative Planningmentioning

confidence: 99%

Surgical strategies for pediatric epilepsy

Guan

Karsy

Ducis³

et al. 2016

Transl. Pediatr.

View full text Add to dashboard Cite

Pediatric epilepsy is a debilitating condition that impacts millions of patients throughout the world. Approximately 20-30% of children with recurrent seizures have drug-resistant epilepsy (DRE).For these patients, surgery offers the possibility of not just seizure freedom but significantly improved neurocognitive and behavioral outcomes. The spectrum of surgical options is vast, ranging from outpatient procedures such as vagus nerve stimulation to radical interventions including hemispherectomy. The thread connecting all of these interventions is a common goal-seizure freedom, an outcome that can be achieved safely and durably in a large proportion of patients. In this review, we discuss many of the most commonly performed surgical interventions and describe the indications, complications, and outcomes specific to each.

show abstract

Usefulness of intracranial EEG in the decision process for epilepsy surgery

Cited by 50 publications

References 35 publications

Influence analysis for high-dimensional time series with an application to epileptic seizure onset zone detection

Influence analysis for high-dimensional time series with an application to epileptic seizure onset zone detection

Evaluation of Algorithms for Intracranial EEG (iEEG) Source Imaging of Extended Sources: Feasibility of Using iEEG Source Imaging for Localizing Epileptogenic Zones in Secondary Generalized Epilepsy

Surgical strategies for pediatric epilepsy

Contact Info

Product

Resources

About