Usefulness of electron beam computed tomography scanning for distinguishing ischemic from nonischemic cardiomyopathy

Budoff, Matthew J.; Shavelle, David M.; Lamont, Daniel H; Kim, H.Tina; Akinwale, Pamela; Kennedy, John M.; Brundage, Bruce H.

doi:10.1016/s0735-1097(98)00387-8

Cited by 95 publications

(37 citation statements)

References 34 publications

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“…One large study of 120 patients with heart failure of unknown etiology demonstrated that the presence of CACP was associated with 99% sensitivity for ischemic cardiomyopathy. 93 Another study demonstrated similarly high sensitivity using dual CT to differentiate ischemic from nonischemic cardiomyopathy. 94 Direct comparison studies have demonstrated this methodology to be more accurate than echocardiography and MPS techniques.…”

Section: Ct Coronary Calcium and Symptomatic Patientsmentioning

confidence: 93%

Assessment of Coronary Artery Disease by Cardiac Computed Tomography

Budoff¹,

Achenbach²,

Blumenthal³

et al. 2006

Circulation

1,233

382

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Section: Ct Coronary Calcium and Symptomatic Patientsmentioning

confidence: 93%

Assessment of Coronary Artery Disease by Cardiac Computed Tomography

Budoff¹,

Achenbach²,

Blumenthal³

et al. 2006

Circulation

1,233

382

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“…Asymptomatic patients without CAC are considered to be low risk, and coronary CT angiography is not recommend in this group 34) . It has also been reported that the CAC score positively correlates with the number of coronary vessels affected by CAD, even in patients with proven CAD 35) , while an elevated CAC score is associated with higher morbidity and mortality rates 36) . Nevertheless, the general use of CAC scoring may be limited, as the high prevalence of CAC results in low specificity for obstructive CAD in symptomatic patients 37) .…”

Section: Cac Score and Cardiovascular Morbidity And Mortality In The mentioning

confidence: 96%

Clinical Implications of the Coronary Artery Calcium Score in Japanese Patients

Yamamoto

Kitagawa

Kihara

2014

JAT

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Coronary artery calcification (CAC) is a well-established surrogate marker of the total burden of coronary atherosclerosis. The CAC score, as measured on coronary computed tomography (CT), is associated with the prevalence of coronary artery disease (CAD) as well as cardiovascular morbidity and mortality. The CAC score is used to reclassify coronary risks in asymptomatic individuals with intermediate risks. However, there are few clinical data regarding the usefulness of the CAC score for identifying high-risk Japanese patients. In this review article, we describe our previous studies of the prognostic value of the CAC score in patients with proven or suspected CAD. In addition, we reanalyzed our previous data for 723 patients with suspected CAD and found both all-cause and cardiovascular disease mortality to be significantly higher among the patients with a CAC score of ≥ 100 than among those with a CAC score of ＜100. Several studies from Japan have also shown that the CAC score is associated with the prevalence of obstructive CAD, as demonstrated on invasive coronary angiography or stress myocardial perfusion imaging. Furthermore, the CAC score provides useful information for performing coronary CT angiography, as asymptomatic patients without CAC are expected to have favorable outcomes. In contrast, the diagnostic accuracy is decreased in patients with a high CAC score (＞400 or 600). In conclusion, the CAC score may have useful clinical applications in symptomatic and asymptomatic Japanese individuals. However, further studies are required to evaluate the prognostic value of this parameter for predicting cardiovascular morbidity and mortality in population-based analyses of asymptomatic Japanese subjects.

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“…Multiple studies have shown the value of CAC scores in excluding CAD as the etiology for heart failure (20)(21)(22). In patients with a diagnosis of heart failure, an Agatston score of 0 has been shown to have 100% specificity in excluding "high-risk CAD," defined as left main coronary artery stenosis or stenosis in at least 2 major epicardial coronary arteries (20,22).…”

Section: Ischemic Versus Nonischemic Cardiomyopathymentioning

confidence: 99%

Cardiac CT Angiography in Congestive Heart Failure

Levine¹,

Hecht²

2015

J Nucl Med

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Cardiac CT angiography has become an important tool for the diagnosis and treatment of congestive heart failure. Differentiation of ischemic from nonischemic cardiomyopathy; evaluation of myocardial perfusion; characterization of hypertrophic cardiomyopathy, left ventricular noncompaction, and arrhythmogenic right ventricular dysplasia; and delineation of congenital heart defects and valvular abnormalities are the primary diagnostic applications. Therapeutic use includes visualization of the coronary venous anatomy for optimal implementation of cardiac resynchronization therapy and evaluation of left ventricular assist devices and transplant vasculopathy.

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Usefulness of electron beam computed tomography scanning for distinguishing ischemic from nonischemic cardiomyopathy

Abstract: This prospective, blinded study indicates that EBCT detected CC accurately and can noninvasively distinguish between cardiomyopathy because of CAD and nonischemic causes of left ventricular dysfunction.

Cited by 95 publications

References 34 publications

Assessment of Coronary Artery Disease by Cardiac Computed Tomography

Assessment of Coronary Artery Disease by Cardiac Computed Tomography

Clinical Implications of the Coronary Artery Calcium Score in Japanese Patients

Cardiac CT Angiography in Congestive Heart Failure

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