2014
DOI: 10.1007/s00586-014-3323-x
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Usefulness of diffusion tensor MR imaging in the assessment of intramedullary changes of the cervical spinal cord in different stages of degenerative spine disease

Abstract: Purpose The aim of this study was to evaluate the usefulness of diffusion tensor imaging (DTI) in the detection of cervical spinal cord integrity alterations in different stages of degenerative spine disease, as well as to compare DTI parameters with selected cervical spinal stenosis measurements. Methods One hundred and thirty-two symptomatic patients (mean age 53.58 years) with different stages of cervical spondylosis and twenty-five control subjects (mean age 45.78 years) were enrolled in the study. DTI was… Show more

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Cited by 42 publications
(28 citation statements)
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“…Our study showed that DTI is 93% more sensitive in detecting early myelopathic changes than the conventional MRI. These results are consistent with Facon et al [2], Kara et al [4], Yoo et al [6], Banaszek et al [8] and Nukala et al [9].…”
Section: Discussionsupporting
confidence: 92%
“…Our study showed that DTI is 93% more sensitive in detecting early myelopathic changes than the conventional MRI. These results are consistent with Facon et al [2], Kara et al [4], Yoo et al [6], Banaszek et al [8] and Nukala et al [9].…”
Section: Discussionsupporting
confidence: 92%
“…A recent systematic review of the literature 59 identified a total of 25 studies that used these techniques to study DCM; 22 used DTI, 3 used MRS, and 1 used MT (in combination with DTI). 10,17,21,22,24,25,30,35,36,39,46,52,53,55,56,58,73,93,104,112,116,124,125,129,136 No clinical studies that used MWF or fMRI were identified. Among the identified DCM studies, the DTI metric fractional anisotropy (FA), a number that ranges from 0 for isotropic diffusion (same in all directions) to 1 for anisotropic (all in 1 direction), seemed to have the strongest results.…”
Section: Studies Using Advanced Mri In Dcmmentioning
confidence: 99%
“…Several authors have described significant changes in DTI parameters in patients with degenerative cervical cord compression (DCCC) . However, certain recent reports indicate an apparent physiological variability in scalar diffusion parameters between cervical spinal cord levels (SCLs) and these parameters may also correlate significantly with age .…”
Section: Introductionmentioning
confidence: 99%