Usefulness of cardiac MRI in the early diagnosis of endomyocardial fibrosis

León, Diego; Martı́n, Marı́a; Corros, Cecília; Santamarta, Elena; Costilla, Serafín; Lambert, José Luis

doi:10.1016/j.repc.2011.12.016

Cited by 20 publications

(14 citation statements)

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“…Taken together, this suggests that cardiac magnetic resonance should be used to monitor spatial and temporal changes during treatment and before major surgical cardiac procedures. 3 , 12 …”

Section: Discussionmentioning

confidence: 99%

Multimodality Imaging in Endomyocardial Fibrosis: An Unusual Etiology of Heart Failure

Velandia-Carrillo

Zuluaga²

2021

CASE

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“…Taken together, this suggests that cardiac magnetic resonance should be used to monitor spatial and temporal changes during treatment and before major surgical cardiac procedures. 3 , 12 …”

Section: Discussionmentioning

confidence: 99%

Multimodality Imaging in Endomyocardial Fibrosis: An Unusual Etiology of Heart Failure

Velandia-Carrillo

Zuluaga²

2021

CASE

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“…Although the mechanism underpinning this increased risk remains unclear, possibilities include obstructive processes associated with parasite carriage [26] and/or more general inflammatory responses inducing pathogenic processes in various vital organs. León et al [27] identified endomyocardial fibrosis in a patient from an endemic area who had L. loa microfilaremia and marked eosinophilia.…”

Section: Discussionmentioning

confidence: 99%

Atypical Clinical Manifestations of Loiasis and Their Relevance for Endemic Populations

Buell

Whittaker

Chesnais

et al. 2019

Open Forum Infectious Diseases

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BackgroundLoiasis is mostly considered a relatively benign infection when compared with other filarial and parasitic diseases, with Calabar swellings and eyeworm being the most common signs. Yet, there are numerous reports in the literature of more serious sequelae. Establishing the relationship between infection and disease is a crucial first step toward estimating the burden of loiasis.MethodsWe conducted a systematic review of case reports containing 329 individuals and detailing clinical manifestations of loiasis with a focus on nonclassical, atypical presentations.ResultsResults indicate a high proportion (47%) of atypical presentations in the case reports identified, encompassing a wide range of cardiac, respiratory, gastrointestinal, renal, neurological, ophthalmological, and dermatological pathologies. Individuals with high microfilarial densities and residing in an endemic country were at greater risk of suffering from atypical manifestations.ConclusionsOur findings have important implications for understanding the clinical spectrum of conditions associated with Loa loa infection, which extends well beyond the classical eyeworm and Calabar swellings. As case reports may overestimate the true rate of atypical manifestations in endemic populations, large-scale, longitudinal clinico-epidemiological studies will be required to refine our estimates and demonstrate causality between loiasis and the breadth of clinical manifestations reported. Even if the rates of atypical presentations were found to be lower, given that residents of loiasis-endemic areas are both numerous and the group most at risk of severe atypical manifestations, our conclusions support the recognition of loiasis as a significant public health burden across Central Africa.

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“…Typically, the acute phase of EMF starts as an acute febrile illness associated with nonspecific symptoms such as dyspnea, itching, and periorbital edema. Clinical signs of pancarditis-with pericardial effusion, myocardial edema, subendocardial necrosis, eosinophilic infiltration, and vasculitis-are often present (2,15). Electrocardiographic findings are usually nonspecific and include low-voltage QRS complex, repolarization abnormalities, conduction disturbances, and arrhythmias.…”

Section: Acute Phasementioning

confidence: 99%

Comprehensive Assessment of Endomyocardial Fibrosis with Cardiac MRI: Morphology, Function, and Tissue Characterization

Carvalho

Azevedo

2020

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Usefulness of cardiac MRI in the early diagnosis of endomyocardial fibrosis

Cited by 20 publications

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Multimodality Imaging in Endomyocardial Fibrosis: An Unusual Etiology of Heart Failure

Multimodality Imaging in Endomyocardial Fibrosis: An Unusual Etiology of Heart Failure

Atypical Clinical Manifestations of Loiasis and Their Relevance for Endemic Populations

Comprehensive Assessment of Endomyocardial Fibrosis with Cardiac MRI: Morphology, Function, and Tissue Characterization

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