Usefulness of cardiac magnetic resonance imaging for detecting acute myocardial infarction in patients with no significant electrocardiogram changes

Takase, Bonpei; Kihara, Teruyoshi; Noya, Kumiko; Abe, Y.; Nagata, Masayoshi; Ohsuzu, Fumitaka

doi:10.1007/s00380-005-0864-2

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…11). Additionally, one could apply the methodology to both types of MRI imaging in order to define subendocardial infarction surrounded by an ischemic region [48][49][50][51]. Additionally, it could be applied to perfusion CT images (Fig.…”

Section: Discussionmentioning

confidence: 99%

The Direct Incorporation of Perfusion Defect Information to Define Ischemia and Infarction in a Finite Element Model of the Left Ventricle

Veress

Fung

Lee

et al. 2015

Journal of Biomechanical Engineering

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This paper describes the process in which complex lesion geometries (specified by computer generated perfusion defects) are incorporated in the description of nonlinear finite element (FE) mechanical models used for specifying the motion of the left ventricle (LV) in the 4D extended cardiac torso (XCAT) phantom to simulate gated cardiac image data. An image interrogation process was developed to define the elements in the LV mesh as ischemic or infarcted based upon the values of sampled intensity levels of the perfusion maps. The intensity values were determined for each of the interior integration points of every element of the FE mesh. The average element intensity levels were then determined. The elements with average intensity values below a user-controlled threshold were defined as ischemic or infarcted depending upon the model being defined. For the infarction model cases, the thresholding and interrogation process were repeated in order to define a border zone (BZ) surrounding the infarction. This methodology was evaluated using perfusion maps created by the perfusion cardiac-torso (PCAT) phantom an extension of the 4D XCAT phantom. The PCAT was used to create 3D perfusion maps representing 90% occlusions at four locations (left anterior descending (LAD) segments 6 and 9, left circumflex (LCX) segment 11, right coronary artery (RCA) segment 1) in the coronary tree. The volumes and shapes of the defects defined in the FE mechanical models were compared with perfusion maps produced by the PCAT. The models were incorporated into the XCAT phantom. The ischemia models had reduced stroke volume (SV) by 18-59 ml. and ejection fraction (EF) values by 14-50% points compared to the normal models. The infarction models, had less reductions in SV and EF, 17-54 ml. and 14-45% points, respectively. The volumes of the ischemic/infarcted regions of the models were nearly identical to those volumes obtained from the perfusion images and were highly correlated (R 2 ¼ 0.99).

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Section: Discussionmentioning

confidence: 99%

The Direct Incorporation of Perfusion Defect Information to Define Ischemia and Infarction in a Finite Element Model of the Left Ventricle

Veress

Fung

Lee

et al. 2015

Journal of Biomechanical Engineering

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Role of contrast-enhanced magnetic resonance imaging in detecting early adverse remodeling and subacute ventricular wall rupture complicating myocardial infarction

et al. 2008

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Ventricular free wall rupture is a catastrophic complication of acute myocardial infarction accounting for a significant proportion of in-patient deaths. Various imaging modalities including two-dimensional and contrast echocardiography have been applied for the early diagnosis of free wall rupture. Cardiac magnetic resonance imaging has recently gained favor as a tool providing accurate diagnosis and visualization of the site of rupture to enable planned surgery. We present a case of subacute free wall rupture where contrast enhanced myocardial resonance imaging helped to delineate the location and extent of the myocardial tear, thereby prompting appropriate surgical intervention.

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Usefulness of cardiac magnetic resonance imaging for detecting acute myocardial infarction in patients with no significant electrocardiogram changes

Cited by 2 publications

References 13 publications

The Direct Incorporation of Perfusion Defect Information to Define Ischemia and Infarction in a Finite Element Model of the Left Ventricle

The Direct Incorporation of Perfusion Defect Information to Define Ischemia and Infarction in a Finite Element Model of the Left Ventricle

Role of contrast-enhanced magnetic resonance imaging in detecting early adverse remodeling and subacute ventricular wall rupture complicating myocardial infarction

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