Usefulness of brain atlases in neuroradiology: Current status and future potential

Nowinski, Wiesław L.

doi:10.1177/1971400916648338

Cited by 15 publications

(18 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An enormous amount of data is produced every day in laboratories worldwide regarding brain mapping, and there are many initiatives to make these data available through public databases. At present, brain atlases are printed, electronic, web-based and some are even available on mobile platforms [ 268 ].…”

Section: Brain Atlasesmentioning

confidence: 99%

Brain Vascular Imaging Techniques

Laviña

2016

IJMS

View full text Add to dashboard Cite

Recent major improvements in a number of imaging techniques now allow for the study of the brain in ways that could not be considered previously. Researchers today have well-developed tools to specifically examine the dynamic nature of the blood vessels in the brain during development and adulthood; as well as to observe the vascular responses in disease situations in vivo. This review offers a concise summary and brief historical reference of different imaging techniques and how these tools can be applied to study the brain vasculature and the blood-brain barrier integrity in both healthy and disease states. Moreover, it offers an overview on available transgenic animal models to study vascular biology and a description of useful online brain atlases.

show abstract

Section: Brain Atlasesmentioning

confidence: 99%

Brain Vascular Imaging Techniques

Laviña

2016

IJMS

View full text Add to dashboard Cite

show abstract

“…More recently, the abovementioned automatic methods are being increasingly applied to detect the brain volumetric alterations [22] in psychiatric diseases such as Alzheimer's disease [23,24], epilepsy [25], Parkinson's disease [26] and bipolar disorder [27,28].…”

Section: Three Approaches Of Vbm Include Standard Optimized and Dartmentioning

confidence: 99%

Comparing VBM and ROI Analyses for Detection of Gray Matter Abnormalities in Patients with Bipolar Disorder using MRI

Seyedi

Jafari

Talaeı

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: With the increasing efforts to a better understanding of psychiatric diseases, detection of brain morphological alterations are necessary. This study compared two methods-voxel based morphometry (VBM) and region of interest (ROI) analyses- to identify significant gray matter changes of patients with bipolar disorder type I (BP I). Methods: The structural MRI were obtained in a total of 50 subjects (25 healthy subjects with a mean age of 34.48±8.32 years as a control group and 25 patients with a mean age of 37.68±10.88 years). We compared the gray matter alteration results obtained by VBM analysis using the DARTEL approach with those obtained using ROI analysis which applies three probabilistic brain atlases namely, hammers, lpba40, and neuromorphometrics atlases. All analyses were conducted via the Computational Anatomy Toolbox (CAT12) implemented in Statistical Parametric Mapping (SPM12) software package. Results: The VBM findings suggested that gray matter reductions in left precentral and right precuneus of the patients compared to healthy subjects(α=0.0005, uncorrected). However, No regions reached the level of significance in ROI analysis using the three atlases (α=0.0005). Conclusion: It can be concluded that VBM analysis seems to be more sensitive to partial changes in this study. If ROI analysis is employed in studies to detect structural brain alterations between groups, it is highly recommended to use VBM analysis besides. Keywords: Voxel-Based Morphometry; ROI Analysis; bipolar disorder; MRI; brain.

show abstract

“…The brain atlases have been employed in a wide scope of applications ranging from medical education to research to clinics as reviewed in (Nowinski 2017a ). One of clinical applications of brain atlases is neuroradiology (Nowinski 2016 ) and, consequently, stroke image handling. The use of human brain atlases in stroke management opens new application avenues which subject is addressed below.…”

Section: Introductionmentioning

confidence: 99%

Human Brain Atlases in Stroke Management

Nowinski

2020

Neuroinform

View full text Add to dashboard Cite

Stroke is a leading cause of death and a major cause of permanent disability. Its management is demanding because of variety of protocols, imaging modalities, pulse sequences, hemodynamic maps, criteria for treatment, and time constraints to promptly evaluate and treat. To cope with some of these issues, we propose novel, patented solutions in stroke management by employing multiple brain atlases for diagnosis, treatment, and prediction. Numerous and diverse CT and MRI scans are used: ARIC cohort, ischemic and hemorrhagic stroke CT cases, MRI cases with multiple pulse sequences, and 128 stroke CT patients, each with 170 variables and one year follow-up. The method employs brain atlases of anatomy, blood supply territories, and probabilistic stroke atlas. It rapidly maps an atlas to scan and provides atlas-assisted scan processing. Atlas-to-scan mapping is application-dependent and handles three types of regions of interest (ROIs): atlas-defined ROIs, atlas-quantified ROIs, and ROIs creating an atlas. An ROI is defined by atlas-guided anatomy or scan-derived pathology. The atlas defines ROI or quantifies it. A brain atlas potential has been illustrated in four atlas-assisted applications for stroke occurrence prediction and screening, rapid and automatic stroke diagnosis in emergency room, quantitative decision support in thrombolysis in ischemic stroke, and stroke outcome prediction and treatment assessment. The use of brain atlases in stroke has many potential advantages, including rapid processing, automated and robust handling, wide range of applications, and quantitative assessment. Further work is needed to enhance the developed prototypes, clinically validate proposed solutions, and introduce them to clinical practice.

show abstract

Usefulness of brain atlases in neuroradiology: Current status and future potential

Cited by 15 publications

References 34 publications

Brain Vascular Imaging Techniques

Brain Vascular Imaging Techniques

Comparing VBM and ROI Analyses for Detection of Gray Matter Abnormalities in Patients with Bipolar Disorder using MRI

Human Brain Atlases in Stroke Management

Contact Info

Product

Resources

About