Usefulness of B-type natriuretic peptide as a noninvasive screening tool for cardiac allograft pathology in pediatric heart transplant recipients

Claudius, Ilene; Lan, Yueh-Tze; Chang, Ruey‐Kang R.; Wetzel, Glenn T.; Alejos, Juan

doi:10.1016/j.amjcard.2003.08.035

Cited by 42 publications

(41 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As demonstrated in the present study, acute rejection may be asymptomatic in children in the postoperative period of heart transplant, and the evaluation of serum BNP levels may be an early indicator of this rejection, especially in the most severe forms such as humoral rejection [27][28][29][30][31] .…”

Section: Discussionmentioning

confidence: 96%

Avaliação do peptídeo natriurético tipo B no diagnóstico de rejeição após transplante cardíaco pediátrico

Sylos¹,

Azeka²,

Kajita³

et al. 2009

Arq. Bras. Cardiol.

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 96%

Avaliação do peptídeo natriurético tipo B no diagnóstico de rejeição após transplante cardíaco pediátrico

Sylos¹,

Azeka²,

Kajita³

et al. 2009

Arq. Bras. Cardiol.

View full text Add to dashboard Cite

show abstract

“…In addition, high BNP level predicts CV morbidity and mortality in symptomatic or asymptomatic adults on dialysis [9,10]. A few reports have examined the meaning of BNP levels in children with congenital heart disease (CHD) [11] or heart transplant (HTx) [12], but its relevance for CV risk stratification in the pediatric population has yet to be determined [13]. Adolescents that are renal transplant recipients (RTRs) or have CKD are at the highest risk for development of CV disease [14].…”

Section: Us Renalmentioning

confidence: 99%

Assessing cardiovascular risk in children with chronic kidney disease. B-type natriuretic peptide: a potential new marker

2005

View full text Add to dashboard Cite

Elevated plasma B-type natriuretic peptide (BNP) level is a hallmark of altered left ventricular (LV) structure and function. Measurement of circulating BNP has proved to be a sensitive and specific diagnostic test for congestive heart failure (CHF) and coronary syndrome in adults. Further, BNP levels constitute a strong predictive marker for future cardiovascular (CV) events. In high CV risk populations, such as adults with hypertension or chronic kidney disease (CKD), increased BNP predicts CV morbidity and mortality in symptomatic or asymptomatic patients. However, caution is needed in interpreting plasma BNP levels, as they increase with both age and decreased renal function. Despite increasing evidence of the value of BNP in the medical literature in adults, data in children are limited to those with congenital heart disease. It is appropriate to analyze the potential application of this tool in children with CKD, a well-known factor for CV disease.

show abstract

“…у детей, перенесших оперативное вмешательство по поводу ВПС, повышение BNP и NT-proBNP также может являться предиктором неблагоприятных исходов [31,44,52,68]. Amirnovin R. и соавт.…”

Section: прогностическая роль натрийуретических пептидовunclassified

“…Обнаружены достовер-ные различия в уровне BNP у пациентов без признаков и с признаками патологии трансплантата. установили, что плазменная концентрация BNP более 100 пг/мл имеет от-рицательное прогностическое значение с чувствительнос-тью 100% [68]. Hsu J., Keller R., Chikovani O.…”

Section: прогностическая роль натрийуретических пептидовunclassified

A clinical importance of natriuretic peptides in pediatric practice

Саперова¹,

Вахлова²

2017

PKiK

View full text Add to dashboard Cite

Natriuretic peptides (NUP) are peptide hormones secreted by cardiomyocytes in response to a volume overload of the heart. Emphasis in the article is placed on the history of NUP discovery, their chemical structure and pathophysiological mechanisms of action. The data on determination of NUP reference values in children with cardiac pathologies are analyzed. A NUP clinical significance in early diagnosis of heart failure in children, including those with congenital heart defects is shown. Also considered is NUP dynamics after surgical correction of congenital heart defects. A conclusion is drawn that NUP play an important prognostic role in evaluating early and late postoperative periods and disease outcomes on a whole.Received 11 October 2016. Accepted 22 December 2016.Funding: The study had no sponsorship.Conflict of interest: The authors declare no conflict of interest.Author contributionsAll authors contributed equally at all stages of the research.

show abstract

Usefulness of B-type natriuretic peptide as a noninvasive screening tool for cardiac allograft pathology in pediatric heart transplant recipients

Cited by 42 publications

References 15 publications

Avaliação do peptídeo natriurético tipo B no diagnóstico de rejeição após transplante cardíaco pediátrico

Avaliação do peptídeo natriurético tipo B no diagnóstico de rejeição após transplante cardíaco pediátrico

Assessing cardiovascular risk in children with chronic kidney disease. B-type natriuretic peptide: a potential new marker

A clinical importance of natriuretic peptides in pediatric practice

Contact Info

Product

Resources

About