Use of Vitamins and their Derivates in the Treatment of Cutaneous Disorders

Abstract

Vitamins represent fundamental substrates for various physiologic functions occurring in human body. This review seeks to highlight their relevance in skin biology and to describe the cutaneous manifestations correlated with their deficiency.

Effect of spinach aqueous extract on wound healing in experimental model diabetic rats with streptozotocin

“…Lack of zinc affects the critical roles that these processes play in healing wounds resulting in a delay of wound healing. 24 The results show that the aqueous spinach extract has a positive effect on the rate of wound healing from the beginning of the study to day 3. However, over time, this effect increases and reaches to its peak.…”

“…Zinc is the co‐factor of RNA and DNA polymerases, and thus, it is involved in the synthesis of DNA, protein synthesis, and proliferation of cells. Lack of zinc affects the critical roles that these processes play in healing wounds resulting in a delay of wound healing . The results show that the aqueous spinach extract has a positive effect on the rate of wound healing from the beginning of the study to day 3.…”

“…Researchers have shown that the lack of vitamin C may lead to very little collagen deposition, decreased angiogenesis, significant bleeding, and, in turn, ineffective wound healing . Vitamin E maintains the membrane mainly through protection of cell membranes against the destruction caused by oxidation . Researchers have also shown that vitamin E may influence the diverse functions of the host immune system.…”

“…23 Vitamin E maintains the membrane mainly through protection of cell membranes against the destruction caused by oxidation. 24 Researchers have also shown that vitamin E may influence the diverse functions of the host immune system. Because vitamin E is an antioxidant, it may act like a broom against extra free radicals and reduce damage to the wound.…”

“…However, the absence or deficiency of vitamin K may lead to the formation of haematoma within the wound that may impair wound healing and the wound is prone to infection. 24 In a case-control study conducted by Park in 2010, it was observed that a diet containing CLA reduces oxidative and inflammatory markers in the early stages of wound healing. Thus, it would improve cutaneous wound healing.…”