2024
DOI: 10.1016/j.amjms.2024.04.001
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Use of tumor markers in distinguishing lung adenocarcinoma-associated malignant pleural effusion from tuberculous pleural effusion

Ling Ai,
Wenjun Wang,
Jingyuan Li
et al.
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“…This exclusion might reflect the lower prevalence of lung squamous cell carcinoma in this study compared to previous research ( 24 ). pCEA and sCEA are strongly associated with lung adenocarcinoma ( 25 , 26 ), with pCEA being a particularly valuable marker for detecting MPE related to lung cancer ( 27 ). LDH and sNSE have also shown significant associations with lymphoma-related and small-cell lung carcinoma MPEs, respectively, offering reasonable sensitivity and specificity ( 28 , 29 ).…”
Section: Discussionmentioning
confidence: 99%
“…This exclusion might reflect the lower prevalence of lung squamous cell carcinoma in this study compared to previous research ( 24 ). pCEA and sCEA are strongly associated with lung adenocarcinoma ( 25 , 26 ), with pCEA being a particularly valuable marker for detecting MPE related to lung cancer ( 27 ). LDH and sNSE have also shown significant associations with lymphoma-related and small-cell lung carcinoma MPEs, respectively, offering reasonable sensitivity and specificity ( 28 , 29 ).…”
Section: Discussionmentioning
confidence: 99%