Use of trigger tool to identify Adverse Drugs Events in dogs.

Fonseca, Beatriz Cristina de Oliveira; Forgerini, Marcela; Zorzin, Leila Crystina Dias; Martins, Marcelo Rodrigues; Matroianni, Patrícia de Carvalho; Lopes, Angela Ferreira; Cunha, Paulo Henrique Jorge da; Dewulf, Nathalie de Lourdes Souza

doi:10.29374/2527-2179.bjvm109720

Cited by 1 publication

(1 citation statement)

References 24 publications

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“…Taking into account the scenario of polypharmacy and the appearance of gastrointestinal disturbances, a trigger tool system for the detection of adverse drug events was applied (FONSECA et al, 2020), which led to high suspicion of drug toxicity. On physical examination, the patient presented mild dehydration and weakness.…”

Section: Case Reportmentioning

confidence: 99%

Digoxin for atrial fibrillation: good, but not too good: a case report

Junior

Almeida²,

Santos³

et al. 2022

AVB

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Digoxin is a cardiotonic glycoside that is traditionally used for the treatment of heart failure and atrial fibrillation in humans and animals. However, the use of digoxin is still a challenge in clinical practice due to its narrow therapeutic range and its potential interaction with several drugs, which could facilitate the development of toxicity. A 12-year-old Labrador retriever was referred with a clinical diagnosis of heart failure and atrial fibrillation, anorexia, vomiting, and diarrhea. He had been medicated with digoxin, furosemide, lisinopril, and amiodarone. The patient also showed clinical signs of hip osteoarthritis and received firocoxib for four days. He additionally received drugs for gastrointeritis. The electrocardiogram demonstrated atrial fibrillation and signs of digitalis toxicity. Laboratory examination showed a high concentration of plasma digoxin, and 5 days after withdrawal of the drugs, the symptoms disappeared, as did the digitalis effects seen in the previous electrocardiogram.

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Section: Case Reportmentioning

confidence: 99%