Use of the Pediatric Quality of Life Inventory to Assess the Health-Related Quality of Life in Children with Recurrent Respiratory Papillomatosis

Lindman, Jonathan P.; Lewis, Linda S.; Accortt, Neil A.; Wiatrak, Brian J.

doi:10.1177/000348940511400701

Cited by 40 publications

(38 citation statements)

References 18 publications

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“…Observer (relative or caregiver)-completed assessments are commonly used in pediatric [49][50][51][52][53][54][55][56][57][58][59] and cognitively impaired human populations. [60][61][62][63][64][65][66][67] Although the subjective worlds of young children, demented adults, and dogs are not directly accessible, readily observable behaviors offer a basis for assessments to be made by individuals who are knowledgeable about the subjects.…”

Section: Discussionmentioning

confidence: 99%

Development and psychometric testing of an instrument designed to measure chronic pain in dogs with osteoarthritis

Brown¹,

Boston²,

Coyne³

et al. 2007

ajvr

192

207

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Objective-To develop and psychometrically test an owner self-administered questionnaire designed to assess severity and impact of chronic pain in dogs with osteoarthritis.Sample Population-70 owners of dogs with osteoarthritis and 50 owners of clinically normal dogs.Procedures-Standard methods for the stepwise development and testing of instruments designed to assess subjective states were used. Items were generated through focus groups and an expert panel. Items were tested for readability and ambiguity, and poorly performing items were removed. The reduced set of items was subjected to factor analysis, reliability testing, and validity testing.Results-Severity of pain and interference with function were 2 factors identified and named on the basis of the items contained in them. Cronbach's α was 0.93 and 0.89, respectively, suggesting that the items in each factor could be assessed as a group to compute factor scores (ie, severity score and interference score). The test-retest analysis revealed κ values of 0.75 for the severity score and 0.81 for the interference score. Scores correlated moderately well (r = 0.51 and 0.50, respectively) with the overall quality-of-life (QOL) question, such that as severity and interference scores increased, QOL decreased. Clinically normal dogs had significantly lower severity and interference scores than dogs with osteoarthritis. Conclusions and Clinical Relevance-A psychometrically sound instrument was developed.Responsiveness testing must be conducted to determine whether the questionnaire will be useful in reliably obtaining quantifiable assessments from owners regarding the severity and impact of chronic pain and its treatment on dogs with osteoarthritis.It is crucial to have quantitative measures of chronic pain that are valid and reliable in clinical patients to enable development and testing of interventions (such as drugs or surgical procedures) designed to reduce such pain. In the past, studies designed to test the efficacy of interventions intended to decrease chronic pain in dogs with osteoarthritis have relied heavily on a veterinarian's assessment of lameness supported by values generated through gait analysis by use of a force plate. When collected properly, data on gait analysis offer an objective measure that can be reliably monitored over time; however, it can be extremely time consuming, requires specialized equipment, and relies on relatively strict inclusion criteria. In addition, these measures only evaluate an animal at 1 specific point in NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author Manuscript time, and weight bearing on an affected limb is only 1 part of the much larger picture of chronic pain in dogs with osteoarthritis. [1][2][3][4][5] When an owner brings a dog to a veterinarian with a concern that the dog has signs of a chronic painful condition, they report a number of behaviors that they attribute to the painful condition (eg, no longer climbs stairs or jumps onto the bed). In monitoring the progression of the dog's cond...

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Section: Discussionmentioning

confidence: 99%

Development and psychometric testing of an instrument designed to measure chronic pain in dogs with osteoarthritis

Brown¹,

Boston²,

Coyne³

et al. 2007

ajvr

192

207

View full text Add to dashboard Cite

show abstract

“…In a report from the Istituto Superiore di Sanita’ , utilities for the Italian general population were assumed equal to the US population, thus the same assumption was used in the model [52]. Disease-related utilities were collected from the BEST II study [22] for all the diseases except for recurrent respiratory papillomatosis which was collected from Lindman et al [53]. and are summarized in Table 2.…”

Section: Methodsmentioning

confidence: 99%

Cost-effectiveness analysis of the nine-valent HPV vaccine in Italy

Mennini

Bonanni

Bianic³

et al. 2017

Cost Eff Resour Alloc

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BackgroundIn Italy HPV vaccination with the quadrivalent vaccine (Gardasil®) is offered actively and free of charge to girls aged 12 since 2007. A nine-valent vaccine (Gardasil 9®) received the European market authorization in 2015 to protect, with only 2 doses, against around 90% of all HPV positive cancers, over 80% of high-grade precancerous lesions and 90% of genital warts caused by HPV types 6/11.MethodsA dynamic transmission model simulating the natural history of HPV-infections was calibrated to the Italian setting and used to estimate costs and QALYs associated with vaccination strategies. The analyses compared two strategies with the nine-valent vaccine (cervical cancer screening and vaccination in girls only or vaccination in boys and girls) to four alternative strategies (cervical cancer screening and vaccination with quadrialent vaccine in girls only, in both boys and girls, with bivalent vaccine in girls and screening strategy only). The National Health Service perspective was considered.ConclusionThe switch to the nine-valent vaccine in Italy can further reduce the burden associated to cervical cancer and HPV-related diseases and is highly cost-effective.ResultsCompared to the current vaccination program with quadrivalent vaccine, the nine-valent vaccine in a programme including girls and boys shows further reductions of 17% in the incidence of cervical cancer, 35 and 14% in anal cancer for males and females, as well as over a million cases of genital warts avoided after 100 years. The new technology is associated with an ICER of 10,463€ per QALY gained in universal vaccination, decreasing to 4483€ when considering the vaccine switch for girls-only.Electronic supplementary materialThe online version of this article (doi:10.1186/s12962-017-0073-8) contains supplementary material, which is available to authorized users.

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“…The Pediatric Quality of Life Inventory (PedsQL4.0) [5] is one of the measures available for children younger than 4 years. It has been found reliable for healthy children and for those with chronic health problems [7,8], and scores have been reported for children with a wide variety of specific health conditions [9][10][11][12][13][14][15][16][17]. HRQOL is increasingly considered an important outcome measure for very low birth weight (VLBW B1,500 g) children [18,19].…”

Section: Introductionmentioning

confidence: 99%

PedsQL relates to function and behavior in very low and normal birth weight 2- and 3-year-olds from a regional cohort

Palta

Sadek-Badawi

2008

Qual Life Res

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Use of the Pediatric Quality of Life Inventory to Assess the Health-Related Quality of Life in Children with Recurrent Respiratory Papillomatosis

Cited by 40 publications

References 18 publications

Development and psychometric testing of an instrument designed to measure chronic pain in dogs with osteoarthritis

Development and psychometric testing of an instrument designed to measure chronic pain in dogs with osteoarthritis

Cost-effectiveness analysis of the nine-valent HPV vaccine in Italy

PedsQL relates to function and behavior in very low and normal birth weight 2- and 3-year-olds from a regional cohort

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