Use of the Injury Severity Score in head injury

Cooke, R. S.; McNicholl, B; Byrnes, D. P.

doi:10.1016/0020-1383(95)00064-g

Cited by 23 publications

(13 citation statements)

References 9 publications

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“…Head injury is known to be the single largest contributor to trauma center deaths [35]. Other studies have shown that extensive intracranial bleeding requiring neurosurgical intervention is associated with a substantially higher probability of in-hospital mortality in comparison with non-surgical intracranial bleeding [36,37]. Furthermore, whole-body CT patients were significantly younger than selective CT patients.…”

Section: Discussionmentioning

confidence: 99%

Impact of whole-body computed tomography on mortality and surgical management of severe blunt trauma

et al. 2012

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IntroductionThe mortality benefit of whole-body computed tomography (CT) in early trauma management remains controversial and poorly understood. The objective of this study was to assess the impact of whole-body CT compared with selective CT on mortality and management of patients with severe blunt trauma.MethodsThe FIRST (French Intensive care Recorded in Severe Trauma) study is a multicenter cohort study on consecutive patients with severe blunt trauma requiring admission to intensive care units from university hospital trauma centers within the first 72 hours. Initial data were combined to construct a propensity score to receive whole-body CT and selective CT used in multivariable logistic regression models, and to calculate the probability of survival according to the Trauma and Injury Severity Score (TRISS) for 1,950 patients. The main endpoint was 30-day mortality.ResultsIn total, 1,696 patients out of 1,950 (87%) were given whole-body CT. The crude 30-day mortality rates were 16% among whole-body CT patients and 22% among selective CT patients (p = 0.02). A significant reduction in the mortality risk was observed among whole-body CT patients whatever the adjustment method (OR = 0.58, 95% CI: 0.34-0.99 after adjustment for baseline characteristics and post-CT treatment). Compared to the TRISS predicted survival, survival significantly improved for whole-body CT patients but not for selective CT patients. The pattern of early surgical and medical procedures significantly differed between the two groups.ConclusionsDiagnostic whole-body CT was associated with a significant reduction in 30-day mortality among patients with severe blunt trauma. Its use may be a global indicator of better management.

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Section: Discussionmentioning

confidence: 99%

Impact of whole-body computed tomography on mortality and surgical management of severe blunt trauma

et al. 2012

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“…A 15% relative reduction in the prevalence of poor outcome was considered clinically relevant. Review of the literature suggested that 40% to 57% of this population would have a poor outcome 24,25…”

Section: Methodsmentioning

confidence: 99%

Out-of-Hospital Hypertonic Resuscitation Following Severe Traumatic Brain Injury

Bulger¹,

May²,

Brasel³

et al. 2010

JAMA

268

168

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RAUMATIC BRAIN INJURY (TBI) IS the leading cause of death following blunt trauma, and survivors often sustain severe disability. TBI is responsible for the greatest number of potential years of life lost from any cause and carries the highest burden on loss of quality-adjusted life-years among survivors. 1 The primary injury to the brain occurs at the time of impact; however, subsequent compromise of cerebral perfusion can lead to an ischemic insult that extends the primary injury, creating a secondary brain injury. 2 Current therapy following severe TBI is focused on minimizing secondary injury by supporting systemic perfusion and reducing intracranial pressure Author Affiliations are listed at the end of this article.

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“…Clinical variables considered for this study included mechanism of injury, GCS (best in 24 hours) [26], Injury Severity Score (ISS) [27], length of hospital stay (LOS), hospital complications (number) and duration of menstrual cycle disruption (where applicable) were obtained. All women and caregivers (when the patient was unable) were interviewed post-TBI about their reproductive history and menopausal status.…”

Section: Study Design and Participantsmentioning

confidence: 99%

Longitudinal sex and stress hormone profiles among reproductive age and post-menopausal women after severe TBI: A case series analysis

et al. 2016

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Use of the Injury Severity Score in head injury

Cited by 23 publications

References 9 publications

Impact of whole-body computed tomography on mortality and surgical management of severe blunt trauma

Impact of whole-body computed tomography on mortality and surgical management of severe blunt trauma

Out-of-Hospital Hypertonic Resuscitation Following Severe Traumatic Brain Injury

Longitudinal sex and stress hormone profiles among reproductive age and post-menopausal women after severe TBI: A case series analysis

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