Use of the Asthma Control Questionnaire to predict future risk of asthma exacerbation

Meltzer, Eli O.; Busse, William W.; Wenzel, Sally E.; Belozeroff, Vasily; Weng, Haoling H.; Feng, JingYuan; Chon, Yun; Chiou, Chiun–Fang; Lin, Shao-Lee

doi:10.1016/j.jaci.2010.08.042

Cited by 115 publications

(83 citation statements)

References 26 publications

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“…The concept of achieving 'total asthma control' 5 is 6 important for reducing the future risk of exacerbations [6][7][8] . It is therefore 7 imperative that we have robust procedures for accurate diagnosis, measurement 8 of severity, prediction of future risk, along with appropriate personalised 9 treatments to achieve this goal.…”

Section: Mcid Minimum Clinically Important Difference 46mentioning

confidence: 99%

“…Cowan et al 267 have suggested using a panel of inflammatory biomarkers to better enable 268 prediction of ICS responsiveness in asthma 46 , but delivery of such a test remains 269 the most difficult hurdle. Even simply using the asthma control questionnaire 24 270 itself seems to be a good predictor of future risk 8 . 271 14 272 We believe the strengths of this study are in the cross-section of patients with 273 mild to moderate disease that we commonly see in clinical practice; who 274 additionally use a variety of ICS moieties.…”

mentioning

confidence: 99%

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Inhaled corticosteroid dose response in asthma

Anderson

Short

Jabbal

et al. 2017

Annals of Allergy, Asthma & Immunology

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Section: Mcid Minimum Clinically Important Difference 46mentioning

confidence: 99%

mentioning

confidence: 99%

Inhaled corticosteroid dose response in asthma

Anderson

Short

Jabbal

et al. 2017

Annals of Allergy, Asthma & Immunology

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“…54 To assess the ability of the ACQ to predict future exacerbations, Bateman et al 64 reported a marked increase in the risk of future exacerbations in subjects with ACQ-5 scores of Ն0.75 compared with subjects with ACQ-5 scores of Ͻ0.05. In another study, Meltzer et al 65 reported that with each point increase in the ACQ score, there is a 50% higher risk of exacerbations.…”

Section: Accuracymentioning

confidence: 98%

Asthma Control Assessment Tools

Alzahrani

Becker

2015

Respir Care

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, and they emphasize periodic assessment of asthma control once treatment is established. Accurate assessment of asthma control is difficult due to the complexity of asthma control and due to the limitations in the traditional methods of assessment, such as lung function tests, physician assessment, and patients' self-assessment. Relying solely on the role of lung function tests is insufficient to reflect the status of asthma control, since patients with asthma may have normal spirometry between exacerbations. Clinicians often overestimate the level of asthma control. Similarly, it is not uncommon for patients to overestimate how well their asthma is controlled, and, therefore, they under-report asthma symptoms and fail to recognize the impact that asthma has on their daily life. As a result, several tools have been developed to quantify the level of asthma control, identify patients at risk, and evaluate the effect of asthma management. This review examines the commonly 106RESPIRATORY CARE • JANUARY 2016 VOL 61 NO 1 used asthma control assessment tools in terms of content, psychometric properties, methods of administration, limitations, and ability to reflect the overall status of asthma control, which can aid clinicians in selecting the most appropriate tool for their needs.

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“…Poor symptom control is also strongly associated with an increased risk of asthma exacerbations. [56][57][58] Asthma symptom control should be assessed at every opportunity, including during routine prescribing or dispensing. Directed questioning is important, as the frequency or severity of symptoms that patients regard as unacceptable or bothersome may vary from current recommendations about the goals of asthma treatment, and differs from patient to patient.…”

Section: Assessing Asthma Symptom Controlmentioning

confidence: 99%

“…[56][57][58] However, several additional independent risk factors have been identified, i.e. factors, that, when present, increase the patient's risk of exacerbations even if symptoms are few.…”

Section: Exacerbationsmentioning

confidence: 99%