Use of^99mTc-doxorubicin scintigraphy in females with breast cancer: a pilot study

Estimation of human absorbed dose for 166Ho-PAM: comparison with 166Ho-DOTMP and 166Ho-TTHMP

“…Advances in knowledge: In this work, two separate points have been investigated: (1) human absorbed dose of INTRODUCTION Nowadays, radiopharmaceuticals have widespread applications in the diagnosis and treatment of various diseases. 1,2 The skeleton is one of the most common sites of metastases in several tumours such as prostate (80%), breast and lung carcinomas (50%). 3 On the other hand, multiple myeloma, as a fatal illness arising from plasma cells in the bone marrow, is an aggressive plasma cell malignancy that can entail an occurrence of progressive pain.…”

Anthracyclines

“…This radiochemical, 99m Tc-doxorubicin, localised to mammary tumour lesions in female patients, and is a potential radiopharmaceutical for imaging of breast tumours in patients. [32] In some cases, anthracyclines may be ineffective due to the development of drug resistance. It can either be primary resistance (insensitive response to initial therapy) or acquired resistance (present after demonstrating complete or partial response to treatment).…”