Use of subatmospheric pressure therapy to prevent burn wound progression in human: first experiences

Kamolz, Lars‐Peter; Andel, H.; Haslik, Werner; Winter, W; Meissl, G.; Frey, Manfred

doi:10.1016/j.burns.2003.12.003

Cited by 150 publications

(104 citation statements)

References 22 publications

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“…40 While this study only examined 7 patients, it suggests that NPWT can help prevent progression of acute partial-thickness burns by improving the microcirculation in the ''reversible'' zone of stasis. Other studies have confirmed that NPWT-treated wounds exhibit decreased bacterial counts after 3-4 days of treatment in both animal and human models.…”

Section: Discussionmentioning

confidence: 95%

Negative pressure wound therapy: eleven-year experience at a tertiary care hospital

et al. 2017

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Background: Management of complicated wounds is a reconstructive challenge. A reconstructive surgeon has to be ready to face new challenges every day. Negative pressure wound therapy has revolutionized the management of complex wounds. We are presenting our experience with this wound care modality in the past 11 years.Methods: It was a prospective study conducted from January 2006 to December 2016 on patients having wounds of varied etiologies, who consented to participate in this study. Custom made low cost NPWT was used till definitive wound closure.Results: A total of 568 patients consented to participate in the study during these 11 years. No major complications were seen. Most of these were males (60.73%) in their 3rd and 4th decade. Trauma was the leading cause of wounds in 38.14%, followed by diabetic foot wounds in 21.5%. Ankle and foot was the most common site of wounds (30.92%) followed by leg (24.01%). A total of 322 small, 218 medium and 97 large size dressings were used. Most of the patients improved with the NPWT. No major complications were seen.Conclusions: NPWT is safe, effective and has proved to be revolutionary in managing difficult wounds. With the use of customized low cost NPWT the benefit can be extended to underprivileged population in under developed nations too.

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Section: Discussionmentioning

confidence: 95%

Negative pressure wound therapy: eleven-year experience at a tertiary care hospital

et al. 2017

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“…A few studies describe this mechanism. One article by Kamolz et al [6] presents a clinical case study about seven patients with bilateral burns on the hand. The authors observed an increase of drained fluid and an evident edema reduction in the NPWT-treated side compared to the controlateral side treated with silver sulfadiazine cream [6] .…”

Section: Edema Reductionmentioning

confidence: 99%

Management of negative pressure wound therapy in the treatment of diabetic foot ulcers

Meloni

Izzo

Vainieri

et al. 2015

WJO

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Diabetic foot (DF) is a common complication of diabetes and the first cause of hospital admission in diabetic patients. In recent years several guidelines have been proposed to reinforce the the management of DF with a notable increase in diabetes knowledge and an overall reduction of amputations. Significant improvements have been reached in the treatment of diabetic foot ulcers (DFUs) and nowadays clinicians have several advanced medications to apply for the best local therapy. Among these, negative pressure wound therapy (NPWT) is a useful adjunct in the management of chronic and complex wounds to promote healing and wound bed preparation for surgical procedures such as skin grafts and flap surgery. NPWT has shown remarkable results although its mechanisms of action are not completely understood. In this paper, we offer a complete overview of this medication and its implication in the clinical setting. We have examined literature related to NPWT concerning human, animal and in vitro studies, and we have summarized why, when and how we can use NPWT to treat DFUs. Further we have associated our clinical experience to scientific evidence in the field of diabetic foot to identify a defined strategy that could guide clinician in the use of NPWT approaching to DFUs. Core tip: This paper represents a summary of the mechanism of action of negative pressure wound therapy and its effectiveness. Further, according to scientific findings and our experience, we propose a flow chart about its use addressed to the field of diabetic foot.Meloni M, Izzo V, Vainieri E, Giurato L, Ruotolo V, Uccioli L. Management of negative pressure wound therapy in the treatment of diabetic foot ulcers.

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“…In case of each patient one hand was treated with conventional silver-sulfadiazine while the other was treated with NPWT. The study proved that when using NPWT the progression of burns was significantly less compared to conventional therapy [26]. Because dressing changes can be rather painful an application of a non-adherent wound dressing on the burn wound surface combined with NPWT can be useful [27].…”

Section: Npwt In Burn Therapymentioning

confidence: 99%

Negative Pressure Wound Therapy—An Effective, Minimally Invasive Therapeutic Modality in Burn Wound Management

Nagy¹,

Juhász²

2015

IJCM

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Use of subatmospheric pressure therapy to prevent burn wound progression in human: first experiences

Cited by 150 publications

References 22 publications

Negative pressure wound therapy: eleven-year experience at a tertiary care hospital

Negative pressure wound therapy: eleven-year experience at a tertiary care hospital

Management of negative pressure wound therapy in the treatment of diabetic foot ulcers

Negative Pressure Wound Therapy—An Effective, Minimally Invasive Therapeutic Modality in Burn Wound Management

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