Use of Streptomycin to Combat Contamination of Treponema Pallidum Suspensions in the TPI Test

Streptomycin Sodium Azide and Merthiolate as Bacteriostatic Agents for Use with the Treponema pallidum Immobilization Test

“…The observations presented in this paper confirm the use of streptomycin as a bacteriostat for use with the TPI test as reported by Ledbetter and Cumming (1954). Original data are presented which show that sodium azide and merthiolate are satisfactory bacteriostats for use with the TPI test.…”

“…Bacterial contamination interferes with the ease and accuracy of reading the test and the metabolic or somatic products of certain contaminants produce non-specific immobilization. This report confirms the value of streptomycin as a bacteriostat, as reported by Ledbetter and Cumming (1954), and also shows that sodium azide and merthiolate are satisfactory bacteriostats for use with the TPI test.…”