Use of Scrambler Therapy in Acute Paediatric Pain: A Case Report and Review of the Literature

Congedi, Sabrina; Spadini, Silvia; Pede, Chiara Di; Ometto, Martina; Franceschi, Tatiana; Tommasi, Valentina De; Agosto, Caterina; Lazzarin, Pierina; Benini, Franca

doi:10.1155/2016/2628919

Cited by 6 publications

(7 citation statements)

References 15 publications

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“…Although the mechanism of ST is not yet clear, it may work by “scrambling” afferent pain signals and replacing them with synthetic “non-pain” information via the cutaneous nerves after the application of noninvasive electrodes around the surface of painful areas. [3]…”

Section: Introductionmentioning

confidence: 99%

Scrambler therapy for the treatment of diabetic peripheral neuropathy pain

Lee

Park²,

Park³

et al. 2019

Medicine

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Rationale: Neuropathy secondary to diabetes mellitus often does not respond well to conventional therapy. Scrambler therapy may be an alternative treatment for otherwise intractable neuropathy. Patient concerns: A 45-year-old female complained of bilateral plantar foot pain. She had been treated for diabetes mellitus for 5 years. Oral analgesics did not resolve her pain. Even nerve block therapy did not adequately relieve her pain. Diagnoses: Diabetic peripheral neuropathy. Intervention: Scrambler therapy. Outcome: Pain reduction; the treatment effect was based around the location of the scrambler patch. Lessons: Scrambler therapy is effective for the treatment of diabetic peripheral neuropathy. Moreover, effective pain management can be achieved for patients who complain of general pain of the sole, including the toe, by attaching scrambler patches around the ankle.

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Section: Introductionmentioning

confidence: 99%

Scrambler therapy for the treatment of diabetic peripheral neuropathy pain

Lee

Park²,

Park³

et al. 2019

Medicine

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“…20,28,31 A single pediatric experience described the efficacy of ST for acute pain treatment in a 12-year-old female. 37 No data are present in literature with regard to the efficacy and applicability of ST on NP in CIPN pediatric population.…”

Section: Introductionmentioning

confidence: 99%

“…In recent years, scrambler therapy (ST), a novel electro‐analgesia device, demonstrated encouraging and positive preliminary results in NP; in fact, various trials evaluated the possible role of ST in the treatment of multiple forms of NP in adults, and some studies included exclusively patients with CIPN . A single pediatric experience described the efficacy of ST for acute pain treatment in a 12‐year‐old female . No data are present in literature with regard to the efficacy and applicability of ST on NP in CIPN pediatric population.…”

Section: Introductionmentioning

confidence: 99%

Scrambler therapy efficacy and safety for neuropathic pain correlated with chemotherapy‐induced peripheral neuropathy in adolescents: A preliminary study

Tomasello

Pinto

Mennini

et al. 2018

Pediatric Blood & Cancer

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Based on these preliminary data, ST could be a good choice for adolescents with CIPN for whom pain control is difficult. ST caused total relief or dramatic reduction in CIPN pain and an improvement in quality of life, durable in follow-up. It caused no detected side effects, and can be retrained successfully. Further larger studies should be performed to confirm our promising preliminary data in pediatric patients with cancer.

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“…Electrodes are then attached along the dermatome of the pain area, not the pain sites. [ 30 ] Stimulation was delivered via skin electrodes around the painful area, and proper electrode placement reduced pain. [ 27 , 31 , 32 ] However, since a “glove and stocking” distribution of sensory loss is almost universal in DPN, [ 33 ] it is difficult to determine the appropriate electrode attachment site, which may differ among physicians.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study

Yoo,

Kim,

Chae

et al. 2023

Medicine

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Background: A variety of medications are available to manage painful diabetic peripheral neuropathy (DPN), but the proper treatment remains challenging. Accordingly, various neuromodulation modalities have been used. However, no prospective clinical trials have evaluated the use of scrambler therapy (ST) in painful DPN. This study aimed to explore the long-term effects of ST in managing painful DPN. Methods: The patients received 10 consecutive STs of 45 minutes every 1 to 2 days. The primary outcome was pain score. We measured the visual analog scale (VAS) pain scores at baseline, during ST, immediately after ST, and at 1, 2, 3, and 6 months after ST. The secondary outcomes were Michigan Neuropathy Screening Instrument (MNSI), Semmes-Weinstein monofilament test, and Leeds Assessment of Neuropathic Symptoms and Signs pain scores, which were measured at baseline, immediately after ST, and at 1, 2, 3, and 6 months after ST. Results: VAS scores showed significant improvement at the 8th, 9th, and 10th sessions during ST and 1 month after ST. The MNSI self-report component score was decreased 1 month after the ST. However, all other outcomes did not show significant differences compared to the baseline. Conclusion: ST may have short-term effects and limited long-term effects on painful DPN.

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Use of Scrambler Therapy in Acute Paediatric Pain: A Case Report and Review of the Literature

Cited by 6 publications

References 15 publications

Scrambler therapy for the treatment of diabetic peripheral neuropathy pain

Scrambler therapy for the treatment of diabetic peripheral neuropathy pain

Scrambler therapy efficacy and safety for neuropathic pain correlated with chemotherapy‐induced peripheral neuropathy in adolescents: A preliminary study

Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study

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