Use of response surface methodology to optimize culture medium for production of lipase with Candida sp. 99-125

He, Yang; Tan, Tianwei

doi:10.1016/j.molcatb.2006.02.018

Cited by 80 publications

(59 citation statements)

References 15 publications

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“…The components and the quantities of constituents used in the fermentation medium and cell adsorption conditions varied according to the design of the matrix (He and Tan, 2006).…”

Section: Materials For Cell Adsorptionmentioning

confidence: 99%

Response surface methodology used for statistical optimization of jiean-peptide production by Bacillus subtilis

Xiao-yong

Zhou

et al. 2010

Electron. J. Biotechnol.

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“…The components and the quantities of constituents used in the fermentation medium and cell adsorption conditions varied according to the design of the matrix (He and Tan, 2006).…”

Section: Materials For Cell Adsorptionmentioning

confidence: 99%

Response surface methodology used for statistical optimization of jiean-peptide production by Bacillus subtilis

Xiao-yong

Zhou

et al. 2010

Electron. J. Biotechnol.

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“…Soybean meal as a by-product of the vegetable oil industry could greatly reduce the costs of lipase production. 4,26) The …”

Section: )mentioning

confidence: 99%

“…3) Optimizing the parameters by statistical experimental design, such as Plackett-Burman design and central composite design, can eliminate these limitations of the single-factor optimization process. These methods have been used successfully to optimize and evaluate the effects of process parameters in mesophilic lipase production, [4][5][6][7][8][9][10] but optimization of cold-active lipase production by these methods is very rare.…”

mentioning

confidence: 99%

Optimization of Cold-Active Lipase Production from Psychrophilic BacteriumMoritellasp. 2-5-10-1 by Statistical Experimental Methods

Wang

Zhang

Hou

et al. 2013

Bioscience, Biotechnology, and Biochemistry

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“…Plackett-Burman (P-B) design as a two-level experimental design, requires fewer runs than a comparable fractional design and can be used to identify the more important independent variables from a long list of candidate factors and select them to realize a complete factorial design (He and Tan, 2006). The variables of the culture conditions were coded according to the following equation:…”

Section: Plackett-burman Designmentioning

confidence: 99%

Statistical experimental methods for optimizing the cultivating conditions for Rhodococcus erythropolis

Zhai¹,

Kong²,

Guan³

et al. 2011

Afr. J. Biotechnol.

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Rhodococcus erythropolis was found to effectively degrade aflatoxin B l produced by Aspergillus flavus and Aspergillus parasiticus. However, one problem of concern was the slow growth of this strain. In this study, Plackett-Burman design was used to select the most important variables, namely, temperature, pH, inoculum size, liquid volume, agitation speed and culture time that affected the growth of R. erythropolis. Central composite experimental design and response surface analysis were adopted to derive a statistical model for optimizing the culture conditions. From the obtained results, it can be concluded that the optimum parameters were: temperature, 15.3°C; pH, 5.56; inoculum size, 4%; liquid volume, 70 ml in 250 ml flask; agitation speed, 180 rpm; and culture time, 58.2 h. At this optimum point, the populations of the viable organisms could reach 10 8 colony forming units (CFU)/ml, which was 100 times higher than that incubated under the initial conditions. After 58.2 h incubation in this optimum cultivating conditions, 53.9 ± 2.1% of aflatoxin B 1 was degraded, while only 20.6±1.4% of aflatoxin B 1 was degraded in the initial conditions.

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Use of response surface methodology to optimize culture medium for production of lipase with Candida sp. 99-125

Cited by 80 publications

References 15 publications

Response surface methodology used for statistical optimization of jiean-peptide production by Bacillus subtilis

Response surface methodology used for statistical optimization of jiean-peptide production by Bacillus subtilis

Optimization of Cold-Active Lipase Production from Psychrophilic BacteriumMoritellasp. 2-5-10-1 by Statistical Experimental Methods

Statistical experimental methods for optimizing the cultivating conditions for Rhodococcus erythropolis

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