Use of rectal mucosal grafts in substitution urethroplasty: an early series

Abstract

BackgroundTo evaluate the feasibility of use of rectal mucosal grafts for augmentation urethroplasty.MethodsA series of five patients who underwent rectal mucosal graft urethroplasty for urethral stricture disease were identified. Descriptive statistics were used to describe these patients. Primary endpoints were recurrence of stricture and perioperative morbidity.ResultsFive patients underwent rectal mucosal graft augmentation urethroplasty. Four had a history of prior buccal mucosal graft (BMG) urethroplasty and one had a history of head and neck cancer. Rectal mucosa was noted to be thinner and required more tailoring than buccal mucosa. All patients had patent urethras at time of postoperative retrograde urethrogram. A small diverticulum was noted in one patient with no further sequelae. No complications from rectal mucosal graft harvest were noted. All patients with prior buccal grafting subjectively preferred the rectal graft due to fewer side effects. Subjectively, patients with prior buccal grafts preferred the post-operative recovery following rectal mucosal graft urethroplasty.ConclusionsRectal mucosal graft augmentation urethroplasty is a safe alternative in patients with contraindications to buccal grafting with limited morbidity.

Is colorectal mucosa a reasonable graft alternative to buccal grafts for urethroplasty?: A comparison of graft histology and stretch

“…As an alternative to buccal grafts, colorectal mucosal grafts (CMGs) can be utilized and have recently been shown, in several small series, to successfully treat complex long urethral strictures ( 12 – 15 ). Although CMG outcome analysis is limited by follow-up length, the success rates seem to be similar with both grafts ( 2 , 12 , 13 , 15 , 16 ). At first glance, CMGs seem to have many of the same advantages as BMGs – they are both wet mucosa, hairless and acquired from a hidden donor site.…”

Single-Port Endorobotic Rectal Mucosa Harvest For Urethral Reconstruction

“…1 Colorectal mucosal grafts for urethral reconstruction have been shown to be good alternative donor options in long-segment substitution UP. 2 Circumferential colonic mucosal grafts are rising in popularity as an alternative, despite requiring colonic resection. 3 Supplemental digital content is available for this article.…”