“…• chemotherapy -5% ointment of 5-fluorouracyl for superficial BCC [41], bleomycin [42], interferon α -experimentally in BCC and SCC [43]; • radiation therapy (teleradiotherapy, brachytherapy) -good cosmetic result, cancers of the central part of the face; defects -actinic dermatitis, should be avoided at the location on the eyelids, nose, ear, reserved for patients with contraindications to surgery [44,45]; • cryosurgery -only for small, superficial BCC changes, for the other it is not recommended, freezing with liquid nitrogen or nitrous oxide [46,47]; • photodynamic therapy -give intravenous or topical photosensitizing substance, which, after 24-48 h accumulates in tumor cells, then radiates with the wave length of 630-660 nm or a laser -by photo-oxidation chemical reaction occurs and leads to death of cancer cells. Low efficacy, relapse is characterized by higher histological malignancy [48].…”