Use of pulsed high intensity focused ultrasound to study the response of brain endothelial cells to mechanical injury
Rajwinder Kaur
Abstract:<p>This work investigated the significance of a sublethal primary mechanical injury induced by pulsed high intensity focused ultrasound (pHIFU) and mechanical stretching techniques to mouse brain endothelial cell (bEND.3) nuclei in vitro followed by secondary hypoxia. The lateral size of the pHIFU beam’s focal spot (~ 1.7 mm) was obtained by characterizing the pHIFU system, and the transparency of the membrane on which the cells were to be cultured was determined theoretically and experimentally. Prelimi… Show more
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