Use of propranolol for the treatment infantile hemangiomas in the maxillofacial region

Sadykov, R.R.; Podmelle, Fred; Sadykov, R.; Kasimova, Kamola; Metellmann, H.R.

doi:10.1016/j.ijom.2013.03.015

Cited by 11 publications

(5 citation statements)

References 12 publications

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“…Vercellino et al, 202 who started the administration at 1 mg/ kg/day and increased to 2 mg/kg/day, and Sadykov et al, 203 who started the administration at 2 mg/kg/day, also reported that propranolol was effective.…”

Section: Oral Propranololmentioning

confidence: 99%

Japanese clinical practice guidelines for vascular anomalies 2017

Mimura

Akita

Fujino

et al. 2020

Pediatrics International

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The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine (EBM) techniques and aimed at improvement of the outcomes. Clinical questions (CQs) were decided based on the important clinical issues. For document retrieval, key words for literature searches were set for each CQ and literature published from 1980 to the end of September 2014 was searched in Pubmed, Cochrane Library, and Japana Centra Revuo Medicina (JCRM). The strengths of evidence and recommendations acquired by systematic reviews were determined following the Medical Information Network Distribution System (MINDS) technique. A total of 33 CQs were used to compile recommendations and the subjects included efficacy of resection, sclerotherapy/embolization, drug therapy, laser therapy, radiotherapy, and other conservative treatment, differences in appropriate treatment due to the location of lesions and among symptoms, appropriate timing of treatment and tests, and pathological diagnosis deciding the diagnosis. Thus, the Japanese Clinical Practice Guidelines for Vascular Anomalies 2017 have been prepared as the evidence‐based guidelines for the management of vascular anomalies.

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Section: Oral Propranololmentioning

confidence: 99%

Japanese clinical practice guidelines for vascular anomalies 2017

Mimura

Akita

Fujino

et al. 2020

Pediatrics International

View full text Add to dashboard Cite

show abstract

“…Vercellino et al, 202 who started the administration at 1 mg/ kg per day and increased to 2 mg/kg per day, and Sadykov et al, 203 who started the administration at 2 mg/kg per day, also reported that propranolol was effective.…”

Section: Oral Propranololmentioning

confidence: 99%

Japanese Clinical Practice Guidelines for Vascular Anomalies 2017

Mimura

Akita

Fujino

et al. 2020

The Journal of Dermatology

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The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety and systematizing treatment, employing evidence-based medicine techniques and aimed at improvement of the outcomes. Clinical questions (CQ) were decided based on the important clinical issues. For document retrieval, key words for published work searches were set for each CQ, and work published from 1980 to the end of September 2014 was searched in PubMed, Cochrane Library and Japana Centra Revuo Medicina databases. The strengths of evidence and recommendations acquired by systematic reviews were determined following the Medical Information Network Distribution System technique. A total of 33 CQ were used to compile recommendations and the subjects included efficacy of resection, sclerotherapy/embolization, drug therapy, laser therapy, radiotherapy and other conservative treatment, differences in appropriate treatment due to the location of lesions and among symptoms, appropriate timing of treatment and tests, and pathological diagnosis deciding the diagnosis. Thus, the Japanese Clinical Practice Guidelines for Vascular Anomalies 2017 have been prepared as the evidence-based guidelines for the management of vascular anomalies.

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“…When the search was repeated for studies published between January and July 2016, we retrieved 516 additional results. Following title and abstract screening, we selected 138 studies for full-text review and ultimately included 78 studies in our analysis 1-4,7…”

Section: Resultsmentioning

confidence: 99%

“…Of the 1230 patients reviewed in our study, 613 were treated with systemic antibiotics, 200 with pulsed dye laser, 197 with oral propranolol, 54 with atenolol, 46 with topical timolol, 25 with pulsed dye laser and Nd:YAG laser, 12 with topical becaplermin, 12 with surgical resection, 8 with wound care alone, 5 with captopril, 1 with vincristine, 19 with combination therapies, and 38 with other, less common, treatment modalities (Table 2). 55 Boos and Castelo-Soccio 56 Cante et al 45 Chang and Kang 4 Neri et al 46 Thomas et al 28 Tlougan et al 57 Weibel et al 31 58 Bagazgoitia et al 59 Ben-Zvi and Gass 60 Bernabeu-Wittel et al 61 Betlloch-Mas et al 9 Bouras et al 62 Cavalli et al 13 Gidaris et al 63 Gulati and Jury 10 Hermans et al 64 Hong and Fischer 47 Kim et al 2 Lanoel et al 65 Morais et al 11 Mousa et al 14 Naouri et al 66 Nelson et al 67 Oksiuta et al 68 Pavlakovic et al 15 Saaiq et al 69 Sadykov et al 70 Saint-Jean et al 8 Sans et al 71 Sharma et al 72 Tan et al 12 Thomas et al 73 Tiwari et al 7 Vercellino et al 74 76 Hermosa et al 33 Lacour et al 36 Morelli et al 34 Ward et al 50 Bookout et al 41 Chang et al…”

Section: Discussionmentioning

confidence: 99%

Medical, Surgical, and Wound Care Management of Ulcerated Infantile Hemangiomas: A Systematic Review

et al. 2018

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Ulcerated infantile hemangiomas may present a therapeutic challenge, especially if there is concurrent hemorrhage or infection. The aim of this study was to systematically review the published evidence on the treatment of ulcerated hemangiomas, focusing on wound healing as the outcome of interest. We searched MEDLINE, Embase, SCOPUS, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Web of Science from inception to July 2016. Seventy-seven studies met our inclusion criteria. One study was a randomized controlled trial, 30 were observational studies, and 46 were case reports or case series. There is significant heterogeneity among the methods used. We reviewed 1239 patients in total. Of the 197 treated with oral propranolol, 191 (97.0%) achieved complete ulcer healing. Thirty-one patients failed corticosteroid therapy (oral, intralesional, or topical) and were subsequently successfully treated with other therapies. Surgical resections were typically performed for larger hemangiomas and those causing complications. None of the therapies discussed appear to offer significant advantages over others. Therefore, treatment decisions should be individualized based on location of disease, extent, symptoms, feasibility, cost, and parental preference.

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Use of propranolol for the treatment infantile hemangiomas in the maxillofacial region

Cited by 11 publications

References 12 publications

Japanese clinical practice guidelines for vascular anomalies 2017

Japanese clinical practice guidelines for vascular anomalies 2017

Japanese Clinical Practice Guidelines for Vascular Anomalies 2017

Medical, Surgical, and Wound Care Management of Ulcerated Infantile Hemangiomas: A Systematic Review

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