Use of Proplast II as a subperiosteal implant for the correction of anophthalmic enophthalmos.

Shah, Sunil; Rhatigan, M; Sampath, Raghavan; Yeoman, Chevas; Sunderland, Sydney; Brammer, Robert E.; Leatherbarrow, B

doi:10.1136/bjo.79.9.830

Cited by 16 publications

(8 citation statements)

References 16 publications

(1 reference statement)

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“…They include placement of a primary implant (27,28) or a larger secondary implant (hydroxyapatite (27)(28)(29)(30)(31) or porous polyethylene-Medpor (32,33), placement of silicone in the upper eyelid sulcus, or the injection of room-temperature-vulcanizing silicone on the posterior orbital floor (34,35). Other biocompatible materials have been used, such as Proplast Il as a subperiosteal implant (36), silicone (Silastic) blocks for extraperiorbital implantation (37), or injectable cross-linked collagen (Zyplast) (38).…”

Section: Post-enucleation or Post-evisceration Socket Syndrome (Peess)mentioning

confidence: 99%

Abnormalities of Orbital Volume

Robert

2002

European Journal of Ophthalmology

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New information on the physiopathology and treatment of orbital volumes pathologies is described: 1) In post-enucleation or evisceration socket syndrome placing of synthetic material (HA-TCP) directly in the intraconal orbital fat can correct most of the symptoms. However the best approach is to prevent orbital volume deficiencies during first surgery using an implant large enough to allow a future prosthesis of a volume less than 2 mL. New procedures for placing the implant after enucleation or evisceration are described. 2) In proptosis related to Graves' orbitopathy relative indications are given for orbital decompression by removal of fat or bone.

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Section: Post-enucleation or Post-evisceration Socket Syndrome (Peess)mentioning

confidence: 99%

Abnormalities of Orbital Volume

Robert

2002

European Journal of Ophthalmology

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“…Proplast I, a polymer consisting of vitreous carbon fibres and polytetrafluoroethylene (Teflon®) and its next generation variant Proplast II, a composite of Teflon® polymer and alumina, were reported among others as eye implants in rabbits (Proplast I) and as subperiosteal implants in anophthalmic patients exhibiting no significant foreign body response or extrusion (Barber et al, 1980;Shah et al, 1995). However, several clinical case reports with temporomandibular joint Teflon®-Proplast implants reported exuberant foreign body reactions, implant displacements and fractures.…”

Section: Introductionmentioning

confidence: 99%

Reticulated vitreous carbon: a useful material for cell adhesion and tissue invasion

Reyes²,

Sánchez³

et al. 2010

eCM

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Diverse carbon materials have been used for tissue engineering and clinical implant applications with varying success. In this study, commercially available reticulated vitreous carbon (RVC) foams were tested in vitro and in vivo for compatibility with primary cell adhesion and tissue repair. Pores sizes were determined as 279 ± 98 μm. No hydroxyapatite deposition was detected after immersion of the foams in simulated body fluid. Nonetheless, RVC provided an excellent support for adhesion of mesenchymal stem cells (MSCs) as well as primary chondrocytes without any surface pre-treatment. Live cell quantification revealed neutral behaviour of the material with plastic adhered chondrocytes but moderate cytotoxicity with MSCs. Yet, rabbit implanted foams exhibited good integration in subcutaneous pockets and most importantly, total defect repair in bone. Probably due to the stiffness of the material, incompatibility with cartilage regeneration was found. Interestingly and in contrast to several other carbon materials, we observed a total lack of foreign body reactions. Our results and its outstanding porous interconnectivity and availability within a wide range of pore sizes convert RVC into an attractive candidate for tissue engineering applications in a variety of bone models and for ex vivo cell expansion for regenerative medical applications.

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“…Several Proplast implants II required subsequent removal because of poor motility and, over histopathological examination, were found to be completely avascular and surrounded by a pseudocapsule [170]. Use of Proplast II has been still reported later as a subperiosteal implant for the correction of anophthalmic enophthalmos in patients having poor orbital volume replacement despite the prior insertion of an adequately-sized spherical implant within the orbital socket [171].…”

Section: Porous Quasi-integrated Implantsmentioning

confidence: 99%