Use of procalcitonin and white blood cells as combined predictors of infection in cardiac surgery patients

Gómez, Esteban Moreno; Heredia, María; Jorge, Paulo Afonso Ribeiro; Lorenzo, Mario; Tamayo, Eduardo; Gutiérrez, S. Pedraza; Álvarez, E

doi:10.1186/cc13405

Cited by 1 publication

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“…Sugita et al [8] showed that the preoperative WBC count did not differ between infected and noninfected patients, although the POD1 WBC count was significantly higher in infected patients than in noninfected patients. The study conducted by Gomez et al [9] also showed that the median WBC count was significantly greater in patients with infection than in those without infection during the first 10 postoperative days.…”

Section: Discussionmentioning

confidence: 95%

The Change of Laboratory Tests Could Be Predictive Factors for Infection after McKeown Esophagogastrectomy

Chen

Wen

Zhao

2019

BioMed Research International

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Aim To analyze whether the change of laboratory tests (postoperative day 1 (POD1) minus pre-operation) could be predictive factors for postoperative infection in patients who have undergone McKeown esophagogastrectomy. Methods We retrospectively investigated the clinical data of 358 patients who have undergone McKeown esophagogastrectomy, and divided them into infection and noninfection groups. SPSS 22.0 software was performed for data analysis. Results In the two groups, smoking status (66.7% vs. 42.3%; P = 0.014), male gender (86.1% vs. 72.0%; P < 0.001), hoarseness (23.6% vs. 8.7%; P < 0.001), poor coughing ability (51.4% vs. 9.1%; P < 0.001), the change of WBC count (5.59 ± 4.75 × 109/L vs. 4.51 ± 4.11 × 109/L; P = 0.05), the change of glucose (6.03 ± 3.97 g/L vs. 3.78 ± 3.18 g/L), the change of ALB (−12.83 ± 3.45 g/L vs. −10.69 ± 3.86 g/L), the change of CRE (0.17 ± 19.94 umol/L vs. −4.02 ± 15.40 umol/L, P = 0.047) were significantly different. These factors were assessed using logistic regression analysis, and factors with P ≤ 0.05 in the univariate analysis were entered into multivariate analysis based on the forward stepwise (conditional) method. Poor coughing ability (odds ratio [OR], 11.034, 95% confidence interval [CI], 5.358–22.724), smoking status (OR, 4.218; 95% CI, 2.110–8.431), the change of WBC count (OR, 1.079; 95% CI, 1.000–1.164), the change of serum ALB level (OR, 0.849; 95% CI, 0.772–0.935), and the change of blood glucose levels (OR, 1.237; 95% CI, 1.117–1.371) were determined as independent risk factors for postoperative infection. We established a scoring system based on these 5 factors, and the area under the curve for this predictive model was 0.843 (range, 0.793–0.894); the sensitivity, specificity, and cut-off score were 70.8%, 85.3%, and 2.500, respectively. Conclusion Poor coughing ability, smoking habit, the high change of WBC and blood glucose levels, and low change of serum ALB levels can be used to predict the occurrence of postoperative infections among patients who have undergone McKeown esophagogastrectomy.

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Section: Discussionmentioning

confidence: 95%