Use of Pet/Ct Scanning in Cancer Patients: Technical and Practical Considerations

Griffeth, Landis K.

doi:10.1080/08998280.2005.11928089

Cited by 178 publications

(145 citation statements)

References 9 publications

Supporting

Mentioning

128

Contrasting

Unclassified

Order By: Relevance

“…This approach was used to show that infarcts in SCD can occur in every bone in the body [21]. A radionuclide bone scan usually shows positive results within 48 to 72 hours of onset of symptoms [22]. Nuclear imaging indicates regions of increased metabolic activity (hot spots) by an increased uptake of a radioactive tracer.…”

Section: Bone Scintigraphymentioning

confidence: 99%

Bone Scintigraphy Scanning Safety and Necessity for Silent and Multifocal Osteonecrosis in Sickle Cell Disease

2016

J Hematol Thromb

View full text Add to dashboard Cite

Sickle cell disease is a congenital autosomal recessive disease. The predominant pathophysiological feature is vaso cclusion, which leads to acute and chronic complications. Multifocal and silent progressive osteonecrosis over the whole skeleton is one of the major complications of this disorder, requiring follow-up, prophylaxis, and treatment. Bone scintigraphy scanning is widely used, relatively inexpensive, well-tolerated, and has an accuracy of over 90%. MRI is the gold standard imaging technique, however, it has a higher specificity than bone scintigraphy, but it may require contrast dye, which could be nephrotoxic, as sickle cell disease nephropathy is a common complication in such patients. For screening purposes and follow-up of bone integrity, a bone scan can detect silent and multifocal osteonecrosis without the need for contrast dye, which makes it a safe and necessary tool for bone complication follow-up before the osteonecrotic asymptomatic joints develop to advance stages without being noticed by the patient.

show abstract

Section: Bone Scintigraphymentioning

confidence: 99%

Bone Scintigraphy Scanning Safety and Necessity for Silent and Multifocal Osteonecrosis in Sickle Cell Disease

2016

J Hematol Thromb

View full text Add to dashboard Cite

show abstract

“…F-18 in FDG (fluorodeoxyglucose) which is an analog of glucose has become very important in detection of cancers and the monitoring of progress in their treatment, using PET. The combination of PET scan and computed tomography (CT) scan in a single device provides simultaneous structural and biochemical information (fused images) under almost identical conditions, minimizing the temporal and spatial differences between the two imaging modalities and is called Fusion imaging [11,12].…”

Section: In Diagnostic Aspectsmentioning

confidence: 99%

Radioisotopes: An overview

Maloth¹,

Velpula²,

Ugrappa³

et al. 2014

IJCRI

View full text Add to dashboard Cite

International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations.IJCRI publishes Review Articles, Case Series, Case Reports, Case in Images, Clinical Images and Letters to Editor. Website: www.ijcasereportsandimages.com Radioisotopes: An overviewKotya Naik Maloth, Nagalaxmi Velpula, Sridevi Ugrappa, Srikanth Kodangal ABSTRACTMany elements which found on earth exist in different atomic configurations and are termed isotopes which have same atomic number but differ in their atomic mass. These unstable element decay by emission of energy such isotopes, which emit radiation, are called radioisotopes. Using of these isotopes in various sectors like industries, agriculture, healthcare and research centres has got a great importance at present. In health care sector, these isotopes are used in nuclear medicine as diagnostic and therapeutic modalities. Radionuclide imaging (or functional imaging) is a branch of medicine which provides the only means of assessing physiologic changes that is a direct result of biochemical alterations and is based on the radiotracer method.In nuclear medicine procedures, radionuclides are combined with other chemical compounds or pharmaceuticals to form radiopharmaceuticals. These radiopharmaceuticals, once administered to the patient, can localize to specific organs or cellular receptors. This unique ability of radiopharmaceuticals allows nuclear medicine to diagnose or treat a disease based on the cellular function and physiology rather than relying on the anatomy.(This page in not part of the published article.) to diagnose or treat a disease based on the cellular function and physiology rather than relying on the anatomy.

show abstract

“…There were circumstances where intrinsic limitations of PET/CT lead to erroneous classification by the CAD [28]. For example, there could be false negatives when the uptake malignancy was unexpectedly low due to the small size or necrosis, leading to reduced number of metabolically active cells per voxel; there could be false negatives or false positives where there were significant body movements between the PET and CT scan leading to misregistration.…”

Section: Robustness Of the Algorithmmentioning

confidence: 99%

Automatic detection and classification of nasopharyngeal carcinoma on PET/CT with support vector machine

Khong

Chan

2012

Int J CARS

View full text Add to dashboard Cite

Purpose Positron emission tomography/computed tomography (PET/CT) has established values for imaging of head and neck cancers, including the nasopharyngeal carcinoma (NPC), utilizing both morphologic and functional information. In this paper, we introduce a computerized system for automatic detection of NPC, targeting both the primary tumor and regional nodal metastasis, on PET/CT. Methods Candidate lesions were extracted based on the features from both PET and CT images and a priori knowledge of anatomical features and subsequently classified by a support vector machine algorithm. The system was validated with 25 PET/CT examinations from 10 patients suffering from NPC. Lesions manually contoured by experienced radiologists were used as the gold standard. Results Results showed that the system successfully identified all 53 hypermetabolic lesions larger than 1 cm in size and excluded normal physiological uptake in brown fat, muscles, bone marrow, brain, and salivary glands. Conclusion The system combined both imaging features and a priori clinical knowledge for classification between pathological and physiological uptake. Preliminary results showed that the system was highly accurate and promising for adoption in clinical use.

show abstract

Use of Pet/Ct Scanning in Cancer Patients: Technical and Practical Considerations

Cited by 178 publications

References 9 publications

Bone Scintigraphy Scanning Safety and Necessity for Silent and Multifocal Osteonecrosis in Sickle Cell Disease

Bone Scintigraphy Scanning Safety and Necessity for Silent and Multifocal Osteonecrosis in Sickle Cell Disease

Radioisotopes: An overview

Automatic detection and classification of nasopharyngeal carcinoma on PET/CT with support vector machine

Contact Info

Product

Resources

About