Use of oxytocin in penned sows and its effect on fetal intra-partum asphyxia

Alonso-Spilsbury, M.; Mota-Rojas, Daniel; Martı́nez-Burnes, Julio; Arch, Emilio; Mayagoitia, Alfonso López; Ramírez-Necoechea, R.; Olmos, Adriana; Ortega, María Elena Trujillo

doi:10.1016/j.anireprosci.2003.11.002

Cited by 52 publications

(38 citation statements)

References 25 publications

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“…However, at times it increases the intensity and frequency of contractions in the uterus, which in turn damages the UC (Linneen et al. , 2005), causes greater fetal mortality (Alonso‐Spilsbury et al. , 2004; Mota‐Rojas et al.…”

Section: Introductionmentioning

confidence: 99%

Uterine activity and fetal electronic monitoring in parturient sows treated with vetrabutin chlorhydrate

González-Lozano

Ortega

Becerril-Herrera

et al. 2010

Journal of Veterinary Pharmacology and Therapeutics

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The aims of the study were to characterize the uterine activity in sows treated with vetrabutin chlorhydrate (VC), an uterotonic and muscle-tropic drug during farrowing, and to measure the effects of the drug on piglet neonatal viability. The experiment involved 1478 piglets from 130 Yorkshire-Landrace sows, randomly allotted into two groups. Farrowing monitoring began 12 h after PGF2alpha synchronization. Group 1 was given physiological solution (G1, n = 65); Group 2 was treated with VC (1 mL/60 kg LW) at the initiation of fetal expulsion (G2, n = 65). In spite of the total duration of expulsion being significantly longer (P < 0.0001), approximately 35 min in the VC treatment, VC application at the time the first piglet was expulsed favored the alive birth of at least one more piglet. Even though the pressure in the uterus was similar in both groups, the number and duration of uterus contractions recorded were significantly less (P < 0.0001) in G2, favoring fewer births with acute fetal suffering, compared with that in G1. VC treated group compared with the control group also had fewer (5.01% vs. 24%) alterations in umbilical cords, as well as a lesser incidence of secondary apnea (2.08% vs. 7.46%) and bradycardia (1.94% vs. 7.61%), which favored a significantly higher vitality score (P < 0.002). With the intent to evaluate uterine activity in sows during the farrowing process, we propose using the equation used in human medical practices to calculate Montevideo Units applied to swine obstetrics for the first time.

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Section: Introductionmentioning

confidence: 99%

Uterine activity and fetal electronic monitoring in parturient sows treated with vetrabutin chlorhydrate

González-Lozano

Ortega

Becerril-Herrera

et al. 2010

Journal of Veterinary Pharmacology and Therapeutics

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“…The rate of stillbirths increases from 2.4 to 10.5% when the farrowing time increases from 3 to 8 h (Alonso Spilsbury et al, 2004). Sows with farrowing duration of longer than 5 h have been reported with 1.4 ± 1.8 stillborn piglets whereas sows with duration of farrowing shorter than 5 h had 0.4 ± 0.8 stillborn piglets (Oliviero et al, 2010).…”

Section: Risk Factors Associated With Stillbirth and Mummification Mamentioning

confidence: 99%

“…It was shown that, despite a significant reduction of the farrowing duration, this treatment even increased the stillbirth rate, the number of piglets with ruptured umbilical cord and meconium staining on the skin, and the need for obstetrical intervention (Alonso Spilsbury et al, 2004;MotaRojas et al, 2002MotaRojas et al, , 2006. It was concluded that oxytocin treatment at the onset of parturition (immediately after the birth of the first piglet) increased the myometrial activity and decreased the uterine blood supply that may result in foetal distress.…”

Section: Pharmacological Interventions During Parturitionmentioning

confidence: 99%

“…The percentage of still born varies from 5 to 15% and of them 10% die shortly before farrowing, 75% during farrowing and 15% immediately after farrowing ( (Glastonbury, 1977;Leenhouwers et al, 1999;Van der Lende, 2000;Koketsu et al, 2010). Pre-partum deaths are usually associated with infectious agents whereas intra-partum deaths are related to non-infectious etiological factors (Sprecher et al, 1974;Alonso-Spilsbury et al, 2004) The risk factors associated with stillbirth and mummified fetuses include litter size, infectious diseases, gestation length, parity number, farrowing length, farrowing interval, dystocia, high environmental temperature, body condition score and nutritional deficiencies (Dial et al, 1992;Zaleski and Hacker, 1993;Leenhouwers et al, 1999;Mengelinget al, 2000;Tantasuparuk et al, 2000;Lucia Jret al, 2002;Schneider et al, 2003). Identification of the risk factors has been associated with stillbirth and mummified fetuses.…”

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confidence: 99%

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Still birth and mummification in swine-A review

Raguvaran

Palakkara

Prabakar

et al. 2017

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Mummification is often noticed in pigs compared to other species due to large litter size. The agents responsible for the reproductive failure in sows may lead to a wide range of sequelae, including abortions, stillbirth, mummification, embryonic death. High prolificacy is associated with increased incidence of stillbirths and mummified fetuses. Plethoras of other foetal and maternal factors have been associated with incidence of still birth and mummification. Identification of those risk factors have been associated with stillbirth and mummified fetuses can helps in optimal herd reproductive efficiency.

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“…In several recent studies attempts were made to reduce stillbirth rate by speeding up the delivery process with oxytocin injections immediately after the birth of the first piglet. It was shown that, despite a significant shortening of the expulsive stage, this treatment even increased stillbirth rates, the number of newborn piglets with a ruptured cord, the number of piglets with meconium staining on the skin, and the need for obstetrical intervention (Mota-Rojas et al 2002;Alonso-Spilsbury et al 2004). So the use of oxytocin in cases of uncomplicated farrowings should be avoided.…”

Section: The Piglet During and Immediately After Birthmentioning

confidence: 99%