Use of noninvasive volume assessment methods to predict acute blood loss in spontaneously breathing volunteers

Abstract

Objective The use of noninvasive volume assessment methods to predict acute blood loss in spontaneously breathing patients remains unclear. We aimed to investigate changes in the pleth variability index (PVI), vena cava collapsibility index (VCCI), end-tidal carbon dioxide (EtCO2), pulse pressure (PP), and mean arterial pressure (MAP) in spontaneously breathing volunteers after acute loss of 450 mL blood and passive leg raise (PLR).Methods This prospective observational study enrolled healthy volunteers in the blood donation center of an academic hospital. We measured the PVI, EtCO2, VCCI, MAP, and PP before blood donation; at the 0th and 10th minute of blood donation; and after PLR. The primary outcome was the changes in PVI, EtCO2, VCCI, MAP, and PP.

Evaluation of Hemodynamic Changes and Fluid Response during Anesthesia in Lumbar Disc Hernias with Pleth Variability Index (PVI)

“…Delerme showed that the PVI value decreased significantly after passive leg raising in spontaneously breathing patients, and they concluded that PVI may be valuable in evaluating fluid response [ 13 ]. Tomo and colleagues showed that the PVI value decreased significantly after passive leg raising in spontaneously breathing patients, and they concluded that PVI could detect early hemodynamic changes after acute blood loss [ 14 ].…”