Use of neuromuscular blockade with rocuronium bromide for intubation in cats

Moreno‐Sala, Armando; Ortiz‐Martínez, Raúl; Flores, Arturo Gerardo Valdivia; Torres‐de‐Moreno, María G; Martínez, Armando

doi:10.1111/vaa.12028

Cited by 11 publications

(15 citation statements)

References 28 publications

(32 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In veterinary medicine, rocuronium has been used extensively in dogs, cats, horses and pigs (Dugdale and others 2002, Auer and Mosing 2006, Alderson and others 2007, Auer and others 2007a, b, Mosing and others 2010, Auer and Moens 2011, Duke-Novakovski and others 2012, Moreno-Sala and others 2013) and has not been mentioned as a cause of anaphylaxis to date, suggesting its use to be safe. The present case report describes a potentially life-threatening reaction likely caused by the repeated intravenous administration of rocuronium in a dog.…”

Section: Introductionmentioning

confidence: 99%

Suspected anaphylaxis after intravenous injection of rocuronium in a dog

Küls

Rocchi

Larenza

2016

Vet Record Case Reports

View full text Add to dashboard Cite

A nine-year-old female Yorkshire Terrier weighing 5.8 kg required anaesthesia for a bilateral phacoemulsification to treat diabetic cataracts. Perioperatively, rocuronium bromide was administered intravenously to achieve centralisation of the eye. Immediately after injection of the rocuronium, the dog developed tachycardia, hypertension and bronchospasm. At this time, no association between the rocuronium and the adverse reaction was made due to the lack of reports of such an event in dogs. A second dose was therefore administered once the animal's spontaneous efforts to breathe indicated partial loss of neuromuscular blockade, this time without adverse effects. However, a third dose of rocuronium resulted in similar signs as the first injection, suggesting an association between the rocuronium and the observed reaction. The signs resolved spontaneously and the dog recovered uneventfully in the intensive care unit from where it was discharged 48 hours after the surgery.

show abstract

Section: Introductionmentioning

confidence: 99%

Suspected anaphylaxis after intravenous injection of rocuronium in a dog

Küls

Rocchi

Larenza

2016

Vet Record Case Reports

View full text Add to dashboard Cite

show abstract

“…The use of NMBAs to facilitate intubation in cats is not a new concept; succinylcholine was evaluated for this purpose (Rex ) and, more recently, rocuronium was used (Moreno‐Sala et al. ).…”

Section: Introductionmentioning

confidence: 99%

“…When the same dose was used to assist intubation, mechanical ventilation was needed for 10–28 minutes (Moreno‐Sala et al. ). However, as the effective dose 90 (ED 90 ; the dose depressing twitch by 90%) of rocuronium approximates 0.09 mg kg −1 (Michalek‐Sauberer et al.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevention of laryngospasm with rocuronium in cats: a dose-finding study

Martin‐Flores

Sakai

Portela

et al. 2016

Veterinary Anaesthesia and Analgesia

View full text Add to dashboard Cite

“…2 Both topical lidocaine and intravenous rocuronium have been shown to be similarly effective in facilitating tracheal intubation in cats where initial attempts to intubate were unsuccessful. 3 …”

Section: Discussionmentioning

confidence: 99%

Intubation following high-dose rocuronium in a cat with protracted laryngospasm

Doodnaught

Pang

2017

Journal of Feline Medicine and Surgery Open Reports

View full text Add to dashboard Cite

Case summaryAn 11-year-old spayed female domestic shorthair cat with a history of laryngospasm at induction of general anesthesia presented for dental evaluation and treatment. The cat was premedicated with hydromorphone (0.05 mg/kg) and alfaxalone (0.5 mg/kg) intravenously, pre-oxygenated for 5 mins (3 l/min, face mask) and anesthesia was induced with alfaxalone (to effect) intravenously. Lidocaine (0.1 ml, 2%) was applied topically to the arytenoid cartilages following loss of jaw tone. Laryngospasm was not noted during or immediately following lidocaine application. However, after waiting 60 s for the onset of effect of the topical lidocaine, laryngospasm was apparent. Orotracheal intubation by direct visualization was unsuccessful after four attempts by three anesthetists (with increasing levels of experience). At this point, a failed intubation was declared and the non-depolarising neuromuscular blocking agent rocuronium (1 mg/kg IV) given, resulting in arytenoid abduction and appropriate conditions for intubation. Successful intubation occurred 9 mins after induction of anesthesia. Oxygen was continuously supplemented throughout and arterial hemoglobin saturation with oxygen was never <94%.Relevance and novel informationTo the authors’ knowledge, this is the first report of the use of high-dose rocuronium to successfully resolve prolonged laryngospasm at induction of general anesthesia in a cat. Despite laryngospasm and a delay in achieving orotracheal intubation, low values for arterial hemoglobin saturation with oxygen (indicative of hypoxemia) were not observed, highlighting the benefits of pre-oxygenation and apneic oxygenation. The principles of the Difficult Airway Society 2015 guidelines were followed in managing this difficult intubation.

show abstract

Use of neuromuscular blockade with rocuronium bromide for intubation in cats

Cited by 11 publications

References 28 publications

Suspected anaphylaxis after intravenous injection of rocuronium in a dog

Suspected anaphylaxis after intravenous injection of rocuronium in a dog

Prevention of laryngospasm with rocuronium in cats: a dose-finding study

Intubation following high-dose rocuronium in a cat with protracted laryngospasm

Contact Info

Product

Resources

About