Use of Nano-Sensors of the Interferences between Pb((II) with Each of Mg(II), Zn(II), Mn(II), Ca(II), Co(II) and PO4-3 in Blood Medium: An Electrochemical Study

Abstract

Lead is considered a key element in causing autism disease in children due to the pollution of this dangerous element to human. The aim of this research is to obtain a chemical compound with the effect of inhibiting the oxidation of lead ions on the brain that causes the autism disease. Cyclic voltammetric technique was used to study the effect of interferences between lead ions with selected elements such as Mn(II), Mg(II), Zn(II), Ca(II), PO 4 -3 and Co(II) in blood medium. Multi wall carbon nano tube (MWCNT) which was modified with glassy carbon electrode (GCE) was used as a working electrode sensor in cyclic voltammetric method. The results showed that the oxidation and reduction current peaks of Pb(II) ions in the blood medium appeared at -0.2 and -0.8 V respectively. It was found that Co(II) ions had a significant effect on the Pb(II) ions in blood medium as anti-oxidative reagent by reducing the anodic current peak of Pb(II) with five folds and enhancing the cathodic current peak. But other ions such as Mn(II), Mg(II), Zn(II), Ca(II) and PO 4 -3 reduced both redox current peaks of Pb(II) in blood medium. It means that Co(II) ions acted as a good anti-oxidative reagent in blood medium which reduced the effect of lead ions on brain cells by the blood stream. Hence, cobalt compounds could be used as drugs for treatment of the autism disease in children.

Electrochemical Effect of Omega 3 Fatty Acid in Milk at Different Temperatures by Cyclic Voltammetry

“…1 and its positive effect on inhibiting lead contamination (Radhi, et al, 2016). Studies are continuing in the field of electrochemistry to discover the important effects on the blood composition of various chemical and pharmaceutical compounds (Radhi, et al, 2017;Radhi, et al, 2018;Radhi, et al, 2010;Abdul-Amir, et al, 2017).…”

Electrochemical characterization of micro- and nano-particles of ceftriaxone in human blood serum samples using cyclic voltammetry

“…Currently scientists have been studied the redox process of nano antibiotics to find the mechanism of oxidative effect in whole blood or serum media of in vitro study [1][2][3][4][5][6].…”

Voltammetric study of saffron in blood mediated by modified glassy carbon electrode (GCE) with carbon nanotube (CNT/GCE)

“…Saffron considered being an anti-oxidative reagent, especially in blood medium, which can be studied by electrochemical method using the cyclic voltammetric analysis. This method has been used recently through different research [1][2][3][4][5][6].…”