Use of MRI in the diagnosis of fetal brain abnormalities in utero (MERIDIAN): a multicentre, prospective cohort study

Griffiths, Paul D.; Bradburn, Michael; Campbell, Mike; Cooper, Cindy; Graham, Robert H.; Jarvis, Deborah; Kilby, Mark D.; Mason, Gerald; Mooney, Cara; Robson, Stephen C.; Wailoo, Allan

doi:10.1016/s0140-6736(16)31723-8

Cited by 235 publications

(213 citation statements)

References 15 publications

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“…The reason for having more females present for MRI is likely due to the fact that clinicians knew about the safety of MRI and that women of child-bearing age had no radiation risk while taking MRI scans [6,12] . Consequently, more males were referred for CT scans in view of cost, availability and lesser degree of radiation safety concerns.…”

Section: Discussionmentioning

confidence: 99%

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Appraisal of Imaging Requests and Findings from MRI Scans of Patients at State Specialists Hospital Bauchi

Ogenyi¹,

England²,

Dlama³

et al. 2018

J. appl. health sci.

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Background: MRI plays a vital role in diagnosis of diseases. Objectives:To determine the pattern of imaging requests and findings from MRI scans of patients in the bauchi State Hospital. Methods:A prospective cross-sectional study of MRI request forms and findings of 138 patients was conducted from August 2016 to January 2017. MRI scans were performed using a 0.35T Neusoft MRI scanner and reported by a group of consultant radiologists. Data were analysed using descriptive statistics with the computer software SPSS version 22 (IbM, New York, USA). Results:This study revealed that majority of the MRI requests were for lumbosacral spine examinations (n=84, 60.9%), followed closely by MRI of the brain (n=42, 30.4%) and thirdly shoulder and abdomen examinations with a frequency of 4.3% each. Out of 138 MRI scans studied, intervertebral disc prolapse (n=60, 43.5%) was the commonest finding from MRI scans of patients, the second most prevalent finding was L4-L5 degenerative disc disease (n=12, 8.7%). Intramuscular lipoma and basal ganglia edema had a prevalence of 4.3%. Conclusion:The commonest requests were MRI lumbosacral and, in terms of findings, we found intervertebral disc prolapse, L4-L5 degenerative disc disease, basal ganglia edema and intramuscular lipoma as the major findings from MRI scans in bauchi.

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Section: Discussionmentioning

confidence: 99%

“…Despite the cost of MRI, its safety profile and the ability to provide accurate soft tissue details make it highly indispensable to medicine. A recent study by griffiths et al clearly demonstrated the extended clinical value of MRI in diagnosis of fetal brain abnormalities [6] .…”

Section: Introductionmentioning

confidence: 99%

Appraisal of Imaging Requests and Findings from MRI Scans of Patients at State Specialists Hospital Bauchi

Ogenyi¹,

England²,

Dlama³

et al. 2018

J. appl. health sci.

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“…A recent study demonstrated the diagnostic accuracy of prenatal ultrasound to be around 70% and to be increased to more than 90% by additional intrauterine MRI, already at 18 weeks of gestation. Since in one third of study patients the clinical management was changed after obtaining the MRI results, intrauterine MRI is recommended as soon as possible after ultrasonographic suspicion of fetal brain anomaly [14].…”

Section: Imagingmentioning

confidence: 99%

Surgical Treatment for Neonatal Hydrocephalus: Catheter-Based Cerebrospinal Fluid Diversion or Endoscopic Intervention?

Krause¹,

Panteliadis²,

Hagel³

et al. 2018

OJMN

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Neonatal hydrocephalus can arise from a multitude of disturbances, among them congenital aqueductal stenosis, myelomeningocele or posthemorrhagic complications in preterm infants. Diagnostic work-up comprises transfontanellar ultrasonography, T2 weighted MRI and clinical assessment for rare inherited syndromes. Classification of hydrocephalus and treatment guidelines is based on detailed consensus statements. The recent evidence favors catheter-based cerebrospinal fluid diversion in children below 6 months, but emerging techniques such as neuroendoscopic lavage carry the potential to lower shunt insertion rates. More long-term study results will be needed to allow for individualized, multidisciplinary decision making. This article gives an overview regarding contemporary pathophysiological concepts, the latest consensus statements and most recent technical developments. KeywordsCerebrospinal Fluid, Hydrocephalus, Neonate, Neuroendoscopy, VP-Shunt The Cerebrospinal Fluid SystemThe cerebrospinal fluid (CSF) system provides mechanical protection of the brain against mild trauma, is involved in nutrient supply and waste removal, and plays a role in the circadian rhythm [1]. In humans it comprises 4 cavities in the brain, the ventricles, which normally take up about 20% of the CSF. In addition, How to cite this paper: Krause, M., Panteliadis, C.P., Hagel, C., Hirsch, F.W., Thome HydrocephalusHydrocephalus is a disbalance between CSF production and resorption. Clinical PresentationMost children with hydrocephalus suffer from a chronic disease with a rather slow progress of symptoms. Only 10% -15% of newborns with hydrocephalus show signs of elevated intracranial pressure [11].In preterm infants, hydrocephalic growth of the neurocranium is preceded by an ultrasonographically detectable enlargement of the ventricles. At this time, the endochondral bone formation of the skull fragments still allows for a certain flexibility and the small children often suffer from a multitude of additional regulatory deficits owing to their immaturity. Therefore the signs of increased intracranial pressure such as bradycardia or respiratory insufficiency are less obvious than in older children. In newborns or infants under the age of 2, the crossing of percentiles of the head circumference compared to body height and weight is the most important sign of isolated hydrocephalus [11].Typical concurring symptoms are a tight, bulging anterior fontanel, dehiscence of skull sutures, increased visibility of scalp veins and a huge frontal bone (frontal bossing). Retraction of the upper eye-lids, together with Parinaud's upgaze palsy can lead to the rare, but very impressive sunset phenomenon, with both irises plunging half below the lower eye-lids.A number of hereditary syndromes, which mostly follow a recessive inheritance, are associated with hydrocephalus (Table 2). Thus, pediatric patients suffering from hydrocephalus of unknown etiology should be examined thoroughly for stigmata indicating an inherited disease.In older children acu...

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“…Este bajo rendimiento después de las 24 semanas, es atribuido a la osificación del cráneo y al descenso de la cabeza fetal hacia la pelvis de la madre. Al adicionar la RMF, la exactitud diagnóstica alcanza un 92% para fetos menores de 24 semanas y para los mayores alcanza hasta un 94% 4 .…”

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“…El 85% de los casos de ventriculomegalia están asociados a otras alteraciones. Una de las ventajas de la RMF, es la posibilidad de realizar una evaluación anatómica fetal completa en busca de alteraciones relacionadas en otros sistemas [2][3][4][5] .…”

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Descripción de la experiencia en RM cerebral fetal en Cali - Colombia

Granados

Ospina

2017

Rev. chil. radiol.

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IntroducciónEl primer caso reportado de uso de resonancia magnética durante el embarazo fue en 1983, para confirmar la presencia de acretismo placentario 1 . En las últimas tres décadas la resonancia magnética fetal (RMF) ha revolucionado el diagnóstico en útero de patologías fetales, ya que tiene muchas ventajas sobre la ultrasonografía (US) prenatal, no está limitada por obesidad materna, la posición fetal o la presencia de Cali -Colombia. Rev Chil Radiol 2017; 23(4): 187-192.

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Use of MRI in the diagnosis of fetal brain abnormalities in utero (MERIDIAN): a multicentre, prospective cohort study

Abstract: National Institute for Health Research Health Technology Assessment programme.

Cited by 235 publications

References 15 publications

Appraisal of Imaging Requests and Findings from MRI Scans of Patients at State Specialists Hospital Bauchi

Appraisal of Imaging Requests and Findings from MRI Scans of Patients at State Specialists Hospital Bauchi

Surgical Treatment for Neonatal Hydrocephalus: Catheter-Based Cerebrospinal Fluid Diversion or Endoscopic Intervention?

Descripción de la experiencia en RM cerebral fetal en Cali - Colombia

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